Moreno Gigi A, Mulligan Karen, Huber Caroline, Linthicum Mark T, Dreyfus David, Juday Timothy, Marx Steven E, Gonzalez Yuri Sanchez, Brookmeyer Ron, Lakdawalla Darius N
Precision Health Economics, 11100 Santa Monica Blvd, Ste 500, Los Angeles, CA 90025. E-mail:
Am J Manag Care. 2016 May;22(6 Spec No.):SP236-44.
Hepatitis C virus (HCV) treatment incentives for private payers may be misaligned because payers must bear immediate costs and may not realize long-term benefits. However, these benefits may accrue to future payers, including Medicare. We examined how and to what extent private payers' current HCV treatment coverage decisions impact Medicare's and private payers' future costs.
Discrete-time Markov model.
We modeled HCV disease progression and transmission to simulate the economic and social effects of different private-payer HCV treatment scenarios on Medicare. The model examined differences between a baseline scenario (current practice guidelines) and 2 alternative scenarios that expand treatment coverage. Spillover effects were measured as reduced HCV treatment costs and medical expenditures in Medicare. We calculated the spillover effects and net social value of each scenario (total value of quality-adjusted life-years accrued over time minus cumulative treatment and medical costs).
With expanded HCV treatment coverage, private payers experience reduced medical expenditures in the 3-to-5-year time horizon; however, they still face higher treatment costs. Over a 20-year horizon, private payers experience overall savings of $10 billion to $14 billion after treatment costs. The expansion of coverage by private payers generates positive spillover benefits to Medicare of $0.3 billion to $0.7 billion over a 5-year horizon, and $4 billion to $11 billion over a 20-year horizon.
When private payers increase HCV treatment coverage, they may achieve significant savings while inducing spillover benefits to Medicare. Future savings, however, may not motivate immediate treatment investments among private payers who experience high beneficiary turnover.
针对丙肝病毒(HCV)感染者的治疗激励措施,对于私人医保支付方而言可能并不匹配,因为支付方必须承担即时成本,却可能无法实现长期收益。然而,这些收益可能会惠及包括医疗保险(Medicare)在内的未来支付方。我们研究了私人医保支付方当前的HCV治疗覆盖决策如何以及在多大程度上影响医疗保险(Medicare)和私人医保支付方未来的成本。
离散时间马尔可夫模型。
我们对HCV疾病进展和传播进行建模,以模拟不同私人医保支付方HCV治疗方案对医疗保险(Medicare)的经济和社会影响。该模型研究了基线方案(现行实践指南)与2种扩大治疗覆盖范围的替代方案之间的差异。溢出效应通过医疗保险(Medicare)中降低的HCV治疗成本和医疗支出进行衡量。我们计算了每种方案的溢出效应和净社会价值(随时间累积的质量调整生命年的总价值减去累积的治疗和医疗成本)。
随着HCV治疗覆盖范围的扩大,私人医保支付方在3至5年的时间范围内医疗支出减少;然而,他们仍面临更高的治疗成本。在20年的时间范围内,私人医保支付方在扣除治疗成本后总体节省100亿至140亿美元。私人医保支付方扩大覆盖范围在5年的时间范围内为医疗保险(Medicare)带来0.3亿至0.7亿美元的正向溢出效益,在长达20年的时间范围内带来40亿至110亿美元的效益。
当私人医保支付方增加HCV治疗覆盖范围时,他们可能在实现显著节省的同时,为医疗保险(Medicare)带来溢出效益。然而,未来的节省可能无法促使受益人群更替频繁的私人医保支付方立即进行治疗投资。