与获得性免疫缺陷综合征相关的非霍奇金淋巴瘤：5例报告

Non-Hodgkin's lymphoma associated with the acquired immune deficiency syndrome: a report of five cases.

作者信息

Sebag-Montefiore D, Makepeace A R, Spittle M F, Godfrey-Faussett P

机构信息

Regional Radiotherapy Centre, Mount Vernon Hospital, Northwood, Middlesex, U.K.

出版信息

Radiother Oncol. 1989 Apr;14(4):297-302. doi: 10.1016/0167-8140(89)90141-2.

DOI:10.1016/0167-8140(89)90141-2

PMID:2727317

Abstract

We report a series of five HIV positive patients with histologically proven non-Hodgkin's lymphoma. The paper illustrates the difficulties experienced in both the clinical diagnosis and its histological confirmation. In this series we have confirmed the predominance of aggressive histological variants and the high frequency of extra-nodal involvement. The prognosis despite treatment was poor; only one patient entered complete remission and the mean survival was only 4.3 months.

摘要

我们报告了一组五例经组织学证实为非霍奇金淋巴瘤的HIV阳性患者。本文阐述了临床诊断及其组织学确诊过程中所遇到的困难。在这组病例中，我们证实了侵袭性组织学变异型占主导地位以及结外受累的高频率。尽管进行了治疗，预后仍然很差；只有一名患者实现了完全缓解，平均生存期仅为4.3个月。