Ishiguro Akira, Sasaki Hatoko, Yahagi Naohisa, Kato Hitoshi, Kure Shigeo, Mori Rintaro
Department of Postgraduate Education and Training, National Center for Child Health and Development, Tokyo, Japan.
Department of Health Policy, National Center for Child Health and Development, Tokyo, Japan.
Pediatr Int. 2017 Jan;59(1):74-79. doi: 10.1111/ped.13050. Epub 2016 Sep 9.
A collaborative network for pediatric research has not been fully established in Japan. To identify the network infrastructure, we conducted a survey on the support and education for clinical research currently available in children's hospitals.
In November 2014, a 27-question survey was distributed to 31 hospitals belonging to the Japanese Association of Children's Hospitals and Related Institutions (JACHRI) to assess clinical research support, research education, research achievements, and their expectations.
All the hospitals responded to the survey. Overall, 74.2% of hospitals had clinical research support divisions. Although all hospitals had ethics committees, <30% of the hospitals had a data manager, intellectual property management unit, biostatistician, and English-language editor. Seven hospitals had education programs for clinical research. The number of seminars and workshops for clinical research had significant correlations with the number of physicians (r = 0.927), pediatricians (r = 0.922), and clinical trial management physicians (r = 0.962). There was a significant difference in the number of clinical trials initiated by physicians between hospitals with research education programs and those without (P < 0.01). The number of education programs was significantly correlated with the number of original articles and case reports in English (r = 0.788), and the number of publications in Japanese (r = 0.648). All hospitals recognized the need for a leader to establish a collaborative network for clinical research.
Important factors for creating a collaborative system for pediatric research in Japan were identified. Human resources to support clinical research are a key factor to improve clinical research education and research achievements.
日本尚未完全建立起儿科研究协作网络。为确定网络基础设施，我们对儿童医院目前提供的临床研究支持与教育情况进行了一项调查。
2014年11月，向隶属于日本儿童医院及相关机构协会（JACHRI）的31家医院发放了一份包含27个问题的调查问卷，以评估临床研究支持、研究教育、研究成果及其期望。
所有医院均对调查做出了回应。总体而言，74.2%的医院设有临床研究支持部门。虽然所有医院都有伦理委员会，但不到30%的医院设有数据管理员、知识产权管理部门、生物统计学家和英文编辑。七家医院设有临床研究教育项目。临床研究研讨会和工作坊的数量与医生人数（r = 0.927）、儿科医生人数（r = 0.922）以及临床试验管理医生人数（r = 0.962）存在显著相关性。设有研究教育项目的医院与未设该项目的医院相比，医生发起的临床试验数量存在显著差异（P < 0.01）。教育项目的数量与英文原创文章和病例报告的数量（r = 0.788）以及日文出版物的数量（r = 0.648）显著相关。所有医院都认识到需要一位领导者来建立临床研究协作网络。
确定了在日本创建儿科研究协作系统的重要因素。支持临床研究的人力资源是改善临床研究教育和研究成果的关键因素。
