Lobato-Mendizábal E, Labardini-Méndez J, Gallardo-Rincón D
Rev Invest Clin. 1989 Jan-Mar;41(1):17-24.
40 patients with DMPS were studied and diagnosed at the INNSZ during 1980-1985. Eighteen were males and twenty two females; age average of 55.7 years (17-82), with 72.5% over 50 years old. Their distribution according to the FAB classification was: 55% type I, 10% type II, 27.5% type III, 2.5% type IV and 5% type V. All of them had an anemic syndrome and 47.5% had bled, 52.5% had pancytopenia; there was anemia and thrombocytopenia in 32.5%, anemia and leukopenia in 7.5%, and anemia only in 7.5%. The bone marrow was normocellular in 42.5%, hypercellular in 40% and hypocellular in 17.5%, 45% of the patients survived; 22% achieved a complete remission (CR) and 9 patients (22.5%) died of causes related to DMPS. The rest was lost to follow up.
1980年至1985年期间，40例糖尿病性多神经病（DMPS）患者在匈牙利国家神经病学和卒中研究所（INNSZ）接受研究和诊断。其中18例为男性，22例为女性；平均年龄55.7岁（17 - 82岁），72.5%的患者年龄超过50岁。根据FAB分类，其分布情况为：I型占55%，II型占10%，III型占27.5%，IV型占2.5%，V型占5%。所有患者均有贫血综合征，47.5%的患者有出血症状，52.5%的患者有全血细胞减少；32.5%的患者有贫血和血小板减少，7.5%的患者有贫血和白细胞减少，仅7.5%的患者只有贫血。42.5%的患者骨髓细胞数量正常，40%的患者骨髓细胞增多，17.5%的患者骨髓细胞减少，45%的患者存活；22%的患者达到完全缓解（CR），9例患者（22.5%）死于与DMPS相关的原因。其余患者失访。
