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玻璃体内注射抗血管内皮生长因子后发生纽氏放线菌性眼内炎

ACTINOMYCES NEUII ENDOPHTHALMITIS AFTER INTRAVITREAL ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR INJECTION.

作者信息

Sahni Sakshi, Watson Randee Miller, Sheth Veeral S

机构信息

*Chicago Medical School, Rosalind Franklin University, North Chicago, Illinois; †UIC Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, Chicago, Illinois; and ‡University Retina and Macula Associates, Oak Forest, Illinois.

出版信息

Retin Cases Brief Rep. 2017;11(3):281-282. doi: 10.1097/ICB.0000000000000345.

DOI:10.1097/ICB.0000000000000345
PMID:27280342
Abstract

PURPOSE

To describe a case of acute endophthalmitis caused by Actinomyces neuii after intravitreal anti-vascular endothelial growth factor injection.

METHODS

Observational case report, review of published literature.

RESULTS

A 67-year-old white man with wet age-related macular degeneration developed endophthalmitis secondary to A. neuii on the 10th day after intravitreal anti-vascular endothelial growth factor injection. Both anterior chamber and vitreous cultures were positive for A. neuii. He was treated successfully with intravitreal injection of vancomycin and ceftazidime.

CONCLUSION

This is the first published report of culture-positive endophthalmitis caused by A. neuii after intravitreal injection.

摘要

目的

描述1例玻璃体内注射抗血管内皮生长因子后由纽氏放线菌引起的急性眼内炎病例。

方法

观察性病例报告,回顾已发表的文献。

结果

1例67岁患有湿性年龄相关性黄斑变性的白人男性,在玻璃体内注射抗血管内皮生长因子后第10天发生了由纽氏放线菌引起的眼内炎。前房和玻璃体培养均显示纽氏放线菌阳性。经玻璃体内注射万古霉素和头孢他啶治疗成功。

结论

这是首次发表的关于玻璃体内注射后由纽氏放线菌引起的培养阳性眼内炎的报告。

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引用本文的文献

1
Actinomyces neuii: a case report of a rare cause of acute infective endocarditis and literature review.内乌拟放线菌致急性感染性心内膜炎 1 例报告并文献复习
BMC Infect Dis. 2019 Jun 10;19(1):511. doi: 10.1186/s12879-019-4149-2.