Sako Y, Kim C H, Ishida Y
a Laboratory of Microbiology, Department of Fisheries, Faculty of Agriculture , Kyoto University , Kyoto 606 , Japan.
Biosci Biotechnol Biochem. 1992 Jan;56(4):692-4. doi: 10.1271/bbb.56.692.
To analyze the genetic system of paralytic shellfish poisoning (PSP) toxin production in the dinoflagellate Alexandrium catenella, we examined toxin compositions and mating type of Fl progenies from crosses between algal strains having different toxin compositions. In all strains used, the mole percentage of their toxin composition did not significantly change in any growth phase, although total toxin levels increased rapidly in the early to middle exponential growth phase and then decreased by 95% in the stationary phase. One parental strain produced gonyautoxin (GTX) 4, and C4, while the other produced neosaxitoxin (neoSTX) and saxitoxin (STX) during all growth phases. Fl progenies showed one parental toxin composition and segregated independently with the mating type. These data suggest that A. catenella is a toxin producer and that Mendelian inheritance of toxin profiles occurs in the heterothallic dinoflagellate A. catenella.
为了分析链状亚历山大藻（Alexandrium catenella）中麻痹性贝类毒素（PSP）产生的遗传系统，我们检测了具有不同毒素组成的藻类菌株杂交后代F1的毒素组成和交配型。在所有使用的菌株中，尽管总毒素水平在指数生长早期到中期迅速增加，然后在稳定期下降了95%，但其毒素组成的摩尔百分比在任何生长阶段都没有显著变化。一个亲本菌株在所有生长阶段产生膝沟藻毒素（GTX）4和C4，而另一个亲本产生新石房蛤毒素（neoSTX）和石房蛤毒素（STX）。F1后代表现出一种亲本毒素组成，并与交配型独立分离。这些数据表明链状亚历山大藻是一种毒素产生者，并且在异宗配合的链状亚历山大藻中，毒素谱遵循孟德尔遗传。
