健康男性体内（13）C-异麦芽低聚糖的代谢
Metabolism of (13)C-Isomaltooligosaccharides in Healthy Men.
作者信息
Kohmoto T, Tsuji K, Kaneko T, Shiota M, Fukui F, Takaku H, Nakagawa Y, Ichikawa T, Kobayash S
机构信息
a Research and Development Center, Showa Sangyo Co., Ltd ., Hinode, Funabashi, Chiba 273 , Japan.
b National Institute of Health and Nutrition , Toyama, Shinjuku-ku, Tokyo 162 , Japan.
出版信息
Biosci Biotechnol Biochem. 1992 Jan;56(6):937-40. doi: 10.1271/bbb.56.937.
Isomaltooligosaccharides (IMO), sweeteners derived from corn-starch, selectively promote the growth of bifidobacteria in the human intestine. The metabolic fate of IMO in healthy men was investigated. The expiration rates of excess (13)CO2 and hydrogen of six men were measured while sedentary and while taking physical exercise after the (13)C-labeled IMO intakes. The breath H2 excretion kept at a constant state after IMO ingestion in the sedentary test and increased in the exercise test. The serum glucose and serum insulin increased 30 min after IMO ingestion. The (13)CO2 recoveries were 28.7% in the sedentary test and 60.9% in the exercise test. These recoveries were 70-80% compared those of maltose. These results indicated that a part of IMO was digested and the residual IMO was fermented by intestinal flora. The energy value of IMO might be about 75% of that of maltose.
异麦芽低聚糖（IMO）是一种从玉米淀粉中提取的甜味剂，能选择性地促进人体肠道内双歧杆菌的生长。研究了IMO在健康男性体内的代谢情况。在摄入13C标记的IMO后，分别在静息状态和进行体育锻炼时测量了6名男性呼出的过量（13）CO2和氢气的排出率。在静息试验中，摄入IMO后呼气中H2排出量保持恒定，而在运动试验中则增加。摄入IMO后30分钟，血清葡萄糖和血清胰岛素水平升高。静息试验中（13）CO2回收率为28.7%，运动试验中为60.9%。与麦芽糖相比，这些回收率为70-80%。这些结果表明，一部分IMO被消化，剩余的IMO被肠道菌群发酵。IMO的能量值可能约为麦芽糖的75%。
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