From the Department of Nuclear Medicine and Molecular Imaging, Tata Memorial Hospital, Mumbai, India.
Clin Nucl Med. 2016 Aug;41(8):646-7. doi: 10.1097/RLU.0000000000001265.
AIDS-related dementia complex is the most severe form of cognitive dysfunction in a patient infected with human immunodeficiency virus. The use of FDG PET/CT to diagnose AIDS-related dementia complex has been studied previously and shows various specific metabolic patterns from striatal hypermetabolism in early asymptomatic stage to global hypometabolism in advanced stages. We present a case of a 49-year-old patient with long-standing human immunodeficiency virus infection, where global brain hypometabolism was noted coincidentally on FDG PET/CT done for initial staging of primary pulmonary non-Hodgkin lymphoma.
艾滋病相关痴呆症是感染人类免疫缺陷病毒的患者中最严重的认知功能障碍形式。先前已经研究了使用 FDG PET/CT 来诊断艾滋病相关痴呆症,其显示出从早期无症状阶段的纹状体代谢亢进到晚期的全脑代谢低下等各种特定的代谢模式。我们报告了一例 49 岁的长期感染人类免疫缺陷病毒的患者,在对原发性肺非霍奇金淋巴瘤进行初始分期的 FDG PET/CT 检查中偶然发现全脑代谢低下。