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The contribution of cell cycle to heterogeneity in single-cell RNA-seq data.

作者信息

McDavid Andrew, Finak Greg, Gottardo Raphael

机构信息

Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.

出版信息

Nat Biotechnol. 2016 Jun 9;34(6):591-3. doi: 10.1038/nbt.3498.

Abstract
摘要

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本文引用的文献

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Normalization of RNA-seq data using factor analysis of control genes or samples.
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Modeling bi-modality improves characterization of cell cycle on gene expression in single cells.
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Using control genes to correct for unwanted variation in microarray data.
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