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前瞻性、随机双盲研究:在门诊肩部手术中减少肌间沟神经阻滞容量用于手术麻醉是否能为患者带来当日恢复优势?

Prospective, Randomized Double-Blind Study: Does Decreasing Interscalene Nerve Block Volume for Surgical Anesthesia in Ambulatory Shoulder Surgery Offer Same-Day Patient Recovery Advantages?

作者信息

Maalouf Daniel B, Dorman Shawna M, Sebeo Joseph, Goytizolo Enrique A, Gordon Michael A, Yadeau Jacques T, Dehipawala Sumudu S, Fields Kara

机构信息

From the *Department of Anesthesiology, Hospital for Special Surgery; †Department of Anesthesiology, Perioperative Care, and Pain Medicine, NYU Langone Medical Center; and ‡Department of Biostatistics, Hospital for Special Surgery, New York, NY; ¶Private practice.

出版信息

Reg Anesth Pain Med. 2016 Jul-Aug;41(4):438-44. doi: 10.1097/AAP.0000000000000418.

Abstract

BACKGROUND AND OBJECTIVES

In this randomized double-blind prospective study in patients undergoing shoulder arthroscopy, we compared the effects of ultrasound-guided interscalene nerve block using 20 mL (intervention group) and 40 mL (control group) of a mepivacaine 1.5% and bupivacaine 0.5% mixture (1:1 volume) on ipsilateral handgrip strength and other postoperative end points.

METHODS

One hundred fifty-four patients scheduled for ambulatory shoulder arthroscopy were randomly assigned to receive a single-injection interscalene block under ultrasound guidance with either 40 mL (control) or 20 mL (intervention) and intravenous sedation. The primary outcome was the change in ipsilateral handgrip strength in the postanesthesia care unit (PACU) measured with a dynamometer. Secondary end points were recorded, including negative inspiratory force, incidences of hoarseness and Horner syndrome, time to readiness for discharge from PACU, time to discharge from PACU, patient satisfaction, time to block resolution, and pain scores.

RESULTS

Postoperative handgrip strength was greater in the 20-mL group compared with the 40-mL group (difference in means, 2.3 kg [95% confidence interval, 0.6-4.0 kg]; P = 0.009). A smaller proportion of patients in the intervention group experienced hoarseness postoperatively compared with the control group (odds ratio, 0.26 [95% confidence interval, 0.08-0.82]; P = 0.015). Patient satisfaction and duration of analgesia were similar in both groups.

CONCLUSIONS

When used for surgical anesthesia for shoulder arthroscopies in the ambulatory setting, a 20-mL volume in an ultrasound-guided interscalene block preserves greater handgrip strength on the ipsilateral side in the PACU compared with 40 mL without significant decrease in block success, duration of analgesia, and patient satisfaction.

摘要

背景与目的

在这项针对接受肩关节镜检查患者的随机双盲前瞻性研究中,我们比较了超声引导下使用20毫升(干预组)和40毫升(对照组)的1.5%甲哌卡因与0.5%布比卡因混合液(体积比1:1)进行肌间沟神经阻滞对同侧握力及其他术后终点指标的影响。

方法

154例计划接受门诊肩关节镜检查的患者被随机分配,在超声引导下接受单次注射肌间沟阻滞,分别注射40毫升(对照组)或20毫升(干预组),并给予静脉镇静。主要结局指标是在麻醉后护理单元(PACU)使用测力计测量的同侧握力变化。记录次要终点指标,包括吸气负压、声音嘶哑和霍纳综合征的发生率、从PACU准备出院的时间、从PACU出院的时间、患者满意度、阻滞消退时间和疼痛评分。

结果

与40毫升组相比,20毫升组术后握力更大(平均差异为2.3千克[95%置信区间,0.6 - 4.0千克];P = 0.009)。与对照组相比,干预组术后声音嘶哑的患者比例更小(优势比,0.26[95%置信区间,0.08 - 0.82];P = 0.015)。两组患者的满意度和镇痛持续时间相似。

结论

在门诊环境中用于肩关节镜手术麻醉时,超声引导下肌间沟阻滞使用20毫升的剂量与40毫升相比,在PACU中能使同侧保持更大的握力,且阻滞成功率、镇痛持续时间和患者满意度均无显著下降。

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