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开放性肩部大手术后,0.2%罗哌卡因与0.15%布比卡因用于患者自控肌间沟镇痛对手部运动功能的影响

Patient-controlled interscalene analgesia with ropivacaine 0.2% versus bupivacaine 0.15% after major open shoulder surgery: the effects on hand motor function.

作者信息

Borgeat A, Kalberer F, Jacob H, Ruetsch Y A, Gerber C

机构信息

Department of Anesthesiology, University Hospital of Zurich/Balgrist, Zurich, Switzerland.

出版信息

Anesth Analg. 2001 Jan;92(1):218-23. doi: 10.1097/00000539-200101000-00042.

Abstract

UNLABELLED

We compared the effects of patient-controlled interscalene analgesia with ropivacaine 0.2% and patient-controlled interscalene analgesia (PCIA) with bupivacaine 0.15% on hand grip strength after major open shoulder surgery. Sixty patients scheduled for elective major shoulder surgery were prospectively randomized to receive in a double-blinded fashion either ropivacaine or bupivacaine through an interscalene catheter. Before surgery, all patients received an interscalene block (ISB) with either 40 mL of 0.6% ropivacaine or 40 mL of 0.5% bupivacaine. Six h after ISB, the patients received a continuous infusion of either 0.2% ropivacaine or 0.15% bupivacaine for 48 h. In both groups, the PCIA infusion rate was 5 mL/h plus a bolus of 4 mL with a lockout time of 20 min. Strength in the hand was assessed preoperatively, 24 h, and 48 h after ISB and 6 h after stopping the infusion of local anesthetic. The presence of paresthesia in the fingers was checked. Pain relief was assessed using a visual analog scale; side effects were noted, and the patients rated their satisfaction 54 h after the block. A significant decrease of strength in the hand was observed in the Bupivacaine group 24, 48, and 54 h after ISB (P < 0.05). Paresthesia was more frequently reported in the Bupivacaine group for the second and third fingers 48 h after ISB (P < 0.05) and in the first three fingers 6 h after discontinuation of the local anesthetic infusion (P: < 0.05). The pain score was similar in the two groups at all times, and patient satisfaction was comparable between the two groups. We conclude that the use of the PCIA technique with ropivacaine 0.2% or bupivacaine 0.15% provides a similar pain relief after major shoulder surgery. However, ropivacaine 0.2% is associated with better preservation of strength in the hand and less paresthesia in the fingers.

IMPLICATIONS

We compared the patient-controlled interscalene analgesia technique with ropivacaine 0.2% and bupivacaine 0.15% after major open shoulder surgery. For similar pain control ropivacaine is associated with better preservation of strength in the hand and less paresthesia in the fingers.

摘要

未标注

我们比较了0.2%罗哌卡因患者自控肌间沟镇痛与0.15%布比卡因患者自控肌间沟镇痛(PCIA)对开放性肩部大手术后握力的影响。60例计划进行择期肩部大手术的患者被前瞻性随机分组,以双盲方式通过肌间沟导管接受罗哌卡因或布比卡因。手术前,所有患者均接受了40 mL 0.6%罗哌卡因或40 mL 0.5%布比卡因的肌间沟阻滞(ISB)。ISB后6小时,患者持续输注0.2%罗哌卡因或0.15%布比卡因48小时。两组中,PCIA输注速率均为5 mL/h加4 mL的单次剂量,锁定时间为20分钟。术前、ISB后24小时和48小时以及停止局部麻醉药输注后6小时评估手部力量。检查手指有无感觉异常。使用视觉模拟量表评估疼痛缓解情况;记录副作用,患者在阻滞54小时后对满意度进行评分。在布比卡因组中,ISB后24、48和54小时观察到手部力量显著下降(P<0.05)。在布比卡因组中,ISB后48小时,第二和第三手指感觉异常的报告更为频繁(P<0.05),局部麻醉药输注停止后6小时,前三根手指感觉异常的报告更为频繁(P<0.05)。两组在所有时间点的疼痛评分相似,两组患者的满意度相当。我们得出结论,使用0.2%罗哌卡因或0.15%布比卡因的PCIA技术在肩部大手术后提供了相似的疼痛缓解。然而,0.2%罗哌卡因与更好地保留手部力量和较少的手指感觉异常相关。

启示

我们比较了开放性肩部大手术后0.2%罗哌卡因和0.15%布比卡因的患者自控肌间沟镇痛技术。对于相似的疼痛控制,罗哌卡因与更好地保留手部力量和较少的手指感觉异常相关。

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