1995年至2014年中国成年人2型糖尿病患病率的长期趋势：一项荟萃分析。
Secular trends in the prevalence of type 2 diabetes in adults in China from 1995 to 2014: A meta-analysis.
作者信息
Han Chengyi, Zhang Ming, Luo Xinping, Wang Chongjian, Yin Lei, Pang Chao, Feng Tianping, Ren Yongcheng, Wang Bingyuan, Zhang Lu, Li Linlin, Yang Xiangyu, Zhang Hongyan, Zhao Yang, Zhou Junmei, Xie Zhihui, Zhao Jingzhi, Hu Dongsheng
机构信息
Department of Epidemiology and Health Statistics, College of Public Health, Zhengzhou University, Zhengzhou, China.
Department of Prevention and Health Care, The Affiliated Luohu Hospital of Shenzhen University Health Sciences Center, Shenzhen, China.
出版信息
J Diabetes. 2017 May;9(5):450-461. doi: 10.1111/1753-0407.12440. Epub 2016 Aug 22.
BACKGROUND
The aim of the present study was to estimate trends in the prevalence of type 2 diabetes mellitus (T2DM) in adults in China.
METHODS
A systematic search was conducted for studies of T2DM prevalence in adults in China from 2000 to 2014. Pooled prevalence was calculated by a random-effects model. Subgroup and sensitivity analyses were performed. Chi-squared and Cochran-Mantel-Haenszel tests were used to assess differences among subgroups and pooled prevalence, respectively.
RESULTS
Forty-six studies (data from 1995 to 2014; 1 463 079 adults) were included in the meta-analysis. The overall prevalence of T2DM was 7.9 %. The pooled prevalence overall and by location (urban and rural), gender (male and female), and age category (18-39, 40-59, and ≥60 years) was 4.5 %, 5.1 % and 3.0 %, 4.0 % and 4.2 %, and 1.4 %, 5.0 %, and 10.3 %, respectively, from 1995 to 1999; 6.6 %, 9.3 % and 5.6 %, 7.4 % and 7.5 %, and 1.8 %, 5.9 %, and 12.4 %, respectively, from 2000 to 2004; 10.3 %, 11.8 % and 6.8 %, 10.0 % and 8.6 %, and 2.8 %, 10.3 %, and 20.0 %, respectively, from 2005 to 2009; and 8.3 %, 12.5 % and 7.6 %, 8.6 % and 8.0 %, and 3.5 %, 8.5 %, and 15.3 %, respectively, from 2010 to 2014. The prevalence increased from 5.8 % to 11.6 % with per-capita gross domestic product and differed by diagnostic criteria.
CONCLUSIONS
There was a trend of increasing prevalence of T2DM in adults in China from 1995 to 2009, with a decrease in 2010-14 and a greater increase over time in urban versus rural areas, males versus females, and older versus younger adults.
背景
本研究旨在评估中国成年人2型糖尿病（T2DM）患病率的变化趋势。
方法
对2000年至2014年中国成年人T2DM患病率的研究进行系统检索。采用随机效应模型计算合并患病率。进行亚组分析和敏感性分析。分别使用卡方检验和 Cochr an-Mantel-Haenszel检验评估亚组间差异和合并患病率。
结果
46项研究（数据来自1995年至2014年；1463079名成年人）纳入荟萃分析。T2DM的总体患病率为7.9%。1995年至1999年，总体合并患病率以及按地区（城市和农村）、性别（男性和女性）和年龄组（18 - 39岁、40 - 59岁和≥60岁）划分的患病率分别为4.5%、5.1%和3.0%，4.0%和4.2%，以及1.4%、5.0%和10.3%；2000年至2004年分别为6.6%、9.3%和5.6%，7.4%和7.5%，以及1.8%、5.9%和12.4%；2005年至2009年分别为10.3%、11.8%和6.8%，10.0%和8.6%，以及2.8%、10.3%和20.0%；2010年至2014年分别为8.3%、12.5%和7.6%，8.6%和8.0%，以及3.5%、8.5%和15.3%。患病率随人均国内生产总值从5.8%增至11.6%，且因诊断标准而异。
结论
1995年至2009年中国成年人T2DM患病率呈上升趋势，2010 - 2014年有所下降，且城市与农村、男性与女性、老年人与年轻人相比，随时间推移患病率上升幅度更大。
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