[Disorders of immune system function and their correction in melanomas with regional metastases].

Dysfunction of the thymus and the immune system in patients with melanoma was shown to be in direct correlation with tumor extent. The use of thymosin-like immunomodulator was followed by the most apparent recovery of the parameters studied in patients with localized melanoma resulting in improved clinical course of the disease. In cases of tumor spread into regional lymph nodes, immunologic disorders observed were identical to those registered prior to treatment. Tumor did not disseminate in patients retaining normal immune status.