Moaveni Daria M, Cohn Jennifer H, Hoctor Katherine G, Longman Ryan E, Ranasinghe J Sudharma
From the Departments of *Clinical Anesthesiology and †Obstetrics and Gynecology, University of Miami Miller School of Medicine/Jackson Memorial Hospital, Miami, Florida.
Anesth Analg. 2016 Aug;123(2):402-10. doi: 10.1213/ANE.0000000000001391.
Over the past 40 years, the success of organ transplantation has increased such that female solid organ transplant recipients are able to conceive and carry pregnancies successfully to term. Anesthesiologists are faced with the challenge of providing anesthesia care to these high-risk obstetric patients in the peripartum period. Anesthetic considerations include the effects of the physiologic changes of pregnancy on the transplanted organ, graft function in the peripartum period, and the maternal side effects and drug interactions of immunosuppressive agents. These women are at an increased risk of comorbidities and obstetric complications. Anesthetic management should consider the important task of protecting graft function. Optimal care of a woman with a transplanted solid organ involves management by a multidisciplinary team. In this focused review article, we review the anesthetic management of pregnant patients with solid organ transplants of the kidney, liver, heart, or lung.
在过去40年里,器官移植的成功率有所提高,使得接受实体器官移植的女性能够成功受孕并足月分娩。麻醉医生面临着在围产期为这些高危产科患者提供麻醉护理的挑战。麻醉方面的考虑因素包括妊娠生理变化对移植器官的影响、围产期的移植物功能,以及免疫抑制剂的母体副作用和药物相互作用。这些女性患合并症和产科并发症的风险增加。麻醉管理应考虑保护移植物功能这一重要任务。对接受实体器官移植的女性进行最佳护理需要多学科团队的管理。在这篇重点综述文章中,我们回顾了肾、肝、心或肺实体器官移植的妊娠患者的麻醉管理。