Okawai Hiroaki, Nitta Keiko, Takahashi Kazuhiko, Katahira Yoshiaki, Sonobe Tarou, Fujita Masashi, Nakajima Hiroyuki, Nitta Shin-Ichi
Institute of Development, Aging, and Cancer, Tohoku University, 4-1 Seiryo-machi, Aob-ku, 980-8575, Sendai-shi, Japan.
Department of Cardiovascular Diseases, Tohoku Koisei Nenkin Hospital, 10 Takasago, Hukumuroaza, Miyagino-ku, 983-0005, Sendai-shi, Japan.
J Med Ultrason (2001). 2003 Mar;30(1):45-54. doi: 10.1007/BF02485169.
Dobutamine and dipyridamole stress echocardiographies are both well able to detect myocardial ischemia resulting from coronary diseases by recognizing the regional wall motion abnormality (WMA). Here we report a method for describing WMA in detail. In pharmacological stress echocardiography, because of difficulties in recognizing the two-dimensional pattern, accuracy sometimes depends upon the skill of the operator. Two stroke volumes obtained using the M-mode and Doppler methods were examined to detect abnormal regional cardiac function by the dipyridamole stress test. Stroke volume obtained by the M-modereflects regional cardiac function and that estimated from the outflow using the Doppler methodreflects total cardiac function. These two stroke volumes were compared in normal subjects and patients with coronary-diseases. The results indicated consistent discrepancies between these two stroke volume in the ischemic hearts as a results of coronary stenosis, whereas changes in stroke volumes in the normal subjects showed the same tendency. This method of combining information about the regional and total functions is thus useful in examining the WMA and regional cardiac function, although it can not be applied to subjects whose stroke volume does not increase under stress.
多巴酚丁胺和双嘧达莫负荷超声心动图都能够通过识别局部室壁运动异常(WMA)来检测由冠状动脉疾病导致的心肌缺血。在此我们报告一种详细描述WMA的方法。在药物负荷超声心动图中,由于难以识别二维模式,准确性有时取决于操作者的技术。通过M型和多普勒方法获得的两个每搏输出量,经双嘧达莫负荷试验检测局部心脏功能异常。M型获得的每搏输出量反映局部心脏功能,而通过多普勒方法从流出道估计的每搏输出量反映全心功能。在正常受试者和冠心病患者中比较这两个每搏输出量。结果表明,由于冠状动脉狭窄,在缺血心脏中这两个每搏输出量之间存在一致的差异,而正常受试者中每搏输出量的变化呈现相同趋势。因此,这种结合局部和全心功能信息的方法在检查WMA和局部心脏功能方面是有用的,尽管它不能应用于负荷状态下每搏输出量不增加的受试者。