Friedrich M, Wüstenberg P W, Hinz U, Schröder J, Noack R, Klinkmann H
Zentralinstitut für Ernährung der AdW der DDR, Potsdam-Rehbrücke.
Z Urol Nephrol. 1989 Feb;82(2):105-12.
Rats were fed protein-restricted after unilateral nephrectomy (6.7% casein). Comparatively other animals were fed with experimental diets, at which 20% of the casein have been replaced by Ketosteril or a mixture of hydroxy acid. The constituents of this mixture are in accordance with the molar relation of all Ketosteril components. However, sodium solts of hydroxy acids of leucine, isoleucine and valin replace the corresponding keto acids of Ketosteril. The other components of the mixture consist of free amino acids. The efficiency of protein utilisation was judged by the relation of increased body weight and nitrogen intake. The efficiency of protein utilisation of both supplemented diets is 2.5 times higher compared with the casein diet.
大鼠在单侧肾切除术后喂食蛋白质限制饮食（6.7%酪蛋白）。相比之下，其他动物喂食实验性饮食，其中20%的酪蛋白已被开同或羟酸混合物替代。该混合物的成分符合所有开同成分的摩尔关系。然而，亮氨酸、异亮氨酸和缬氨酸的羟酸钠盐替代了开同相应的酮酸。混合物的其他成分由游离氨基酸组成。通过体重增加与氮摄入量的关系来判断蛋白质利用效率。两种补充饮食的蛋白质利用效率比酪蛋白饮食高2.5倍。
