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[高压氧疗对未纠正及已纠正的实验性脑压迫急性脱臼综合征病程及结局的影响]

[The effect of hyperbaric oxygenation on the course and outcome of acute dislocation syndrome in uncorrected and corrected experimental compression of the brain].

作者信息

Isakov Iu V, Livshits B M

出版信息

Zh Vopr Neirokhir Im N N Burdenko. 1989 Jan-Feb(1):13-6.

PMID:2728759
Abstract

Acute compression-dislocation syndrome of a severe degree was reproduced in rabbits by dosed compression of the brain with an epidurally situated balloon. Animals of the main group were treated by HBO in persisting compression of the brain (series I) and after its correction (series II). Animals of the control group were not treated. HBO had no influence on mortality in series I, a tendency towards reduction of the animals's survival period under the effect of hyperoxia was noted. In series II HBO led to reduction of mortality among rabbits with the severest manifestations of the syndrome and a more frequent and full recovery of animals who survived.

摘要

通过硬膜外放置球囊对兔脑进行定量压迫,复制出重度急性压迫-脱位综合征。主要组动物在脑持续受压时(系列I)以及脑受压纠正后(系列II)接受高压氧治疗。对照组动物未接受治疗。在系列I中,高压氧对死亡率无影响,但注意到在高氧作用下动物存活期有缩短趋势。在系列II中,高压氧使该综合征最严重表现的兔的死亡率降低,且存活动物更频繁、更完全地恢复。

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