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抗血栓治疗与接受腹腔镜胃切除术患者围手术期并发症风险之间的关联。

Associations between antithrombotic therapy and the risk of perioperative complications among patients undergoing laparoscopic gastrectomy.

作者信息

Takahashi Kodai, Ito Hideto, Katsube Toshio, Tsuboi Ayaka, Hashimoto Masatoshi, Ota Emi, Mita Kazuhito, Asakawa Hideki, Hayashi Takashi, Fujino Keiichi

机构信息

Department of Surgery, New-Tokyo Hospital, 1271 Wanagaya Matsudo-city, Chiba, 270-2232, Japan.

出版信息

Surg Endosc. 2017 Feb;31(2):567-572. doi: 10.1007/s00464-016-4998-3. Epub 2016 Jun 10.

Abstract

BACKGROUND

The aim of this study was to identify factors associated with perioperative morbidity among patients who underwent laparoscopic gastrectomy while receiving antithrombotic therapy (ATT).

PATIENTS AND METHOD

This retrospective cohort study included 46 patients (14 females and 32 males) who underwent laparoscopic gastrectomy, including 12 (26.1 %) who received perioperative ATT, between January 2012 and November 2015 in our institution. Among patients receiving only aspirin as antiplatelet therapy, none were on anticoagulation therapy. All patients took aspirin as antiplatelet therapy for cardiac indications. The clinical findings and surgical outcomes of patients who did (ATT group) and did not (control group) receive ATT were compared.

RESULTS

The intraoperative mortality was 0 % for both groups. There was no significant difference in the incidence of postoperative morbidity by univariate analysis between the control and ATT groups (8.8 vs. 8.3 %, p = 0.39).

CONCLUSION

The risk of postoperative morbidity of laparoscopic gastrectomy can be equivalent between the ATT and non-ATT (control) groups.

摘要

背景

本研究旨在确定接受抗血栓治疗(ATT)的患者在接受腹腔镜胃切除术期间与围手术期发病率相关的因素。

患者与方法

这项回顾性队列研究纳入了2012年1月至2015年11月期间在我院接受腹腔镜胃切除术的46例患者(14例女性和32例男性),其中12例(26.1%)接受了围手术期ATT。在仅接受阿司匹林作为抗血小板治疗的患者中,无人接受抗凝治疗。所有患者均因心脏适应症服用阿司匹林作为抗血小板治疗。比较了接受ATT的患者(ATT组)和未接受ATT的患者(对照组)的临床结果和手术结局。

结果

两组的术中死亡率均为0%。对照组和ATT组之间通过单因素分析得出的术后发病率无显著差异(8.8%对8.3%,p = 0.39)。

结论

腹腔镜胃切除术的术后发病风险在ATT组和非ATT(对照)组之间可能相当。

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