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兔正常膝关节和滑膜炎膝关节的淋巴转运

Lymphatic transport from normal and synovitic knees in rabbits.

作者信息

Reimann I, Vittas D, Nielsen S L, Svalastoga E

机构信息

University of Copenhagen, Department of Orthopedics, Herlev Hospital, Denmark.

出版信息

Acta Orthop Scand. 1989 Apr;60(2):185-7. doi: 10.3109/17453678909149250.

DOI:10.3109/17453678909149250
PMID:2728880
Abstract

The resorption pattern of synovial fluid through the lymphatic system from normal and synovitic knee joints in rabbits was studied with 99mtechnetium-rhenium-sulfur colloid injected intraarticularly and monitored for 14 hours with a gamma camera. On the normal side the regional lymph nodes were visualized after 1 hour and after 14 hours still 75 percent activity remained in the knee. In the synovitic knees no lymphatic transport could be detected; and the radiotracer was unstable with rapid liberation of technetium, which was excreted in the urine. This radiolysis was not found in vitro in synovitic joint fluid. The lymphatic transport from normal rabbit knees is low. We found a clear difference in lymphatic transport between normal and synovitic knee joints.

摘要

通过向兔正常膝关节和滑膜炎膝关节内注射99m锝-铼-硫胶体,并使用γ相机监测14小时,研究了滑膜液通过淋巴系统的再吸收模式。在正常侧,1小时后可见区域淋巴结,14小时后膝关节内仍保留75%的活性。在滑膜炎膝关节中,未检测到淋巴转运;放射性示踪剂不稳定,锝迅速释放,并经尿液排出。在滑膜炎关节液的体外实验中未发现这种放射性分解。正常兔膝关节的淋巴转运较低。我们发现正常膝关节和滑膜炎膝关节的淋巴转运存在明显差异。

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