Efficacy of ciprofloxacin in the treatment of various bacterial infections.

The efficacy and safety of ciprofloxacin (500 mg administered every 12 hours) were evaluated in 62 patients enrolled in a prospective, open study. Fifty-three courses in the treatment of 56 infection sites suitable for evaluation were assessed. The infection sites involved were skin and skin structure (28), respiratory tract (21), urinary tract (5), and gastrointestinal tract (2). Bacterial isolates included 16 Pseudomonas aeruginosa, 13 Staphylococcus aureus, and 8 Escherichia coli. Signs and symptoms of infection completely resolved in 46 (82%) of the infection sites. Nine (16%) improved, and one (2%) failed to respond. Ciprofloxacin was well tolerated.