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特应性皮炎:临床内涵,尤其关注免疫受损/易感性遗传和代谢紊乱中伴发的特应性底色。

Atopic Dermatitis: Clinical Connotations, Especially a Focus on Concomitant Atopic Undertones in Immunocompromised/Susceptible Genetic and Metabolic Disorders.

作者信息

Sehgal Virendra N, Khurana Ananta, Mendiratta Vibhu, Saxena Deepti, Srivastava Govind, Aggarwal Ashok K, Chatterjee Kingshuk

机构信息

Dermato Venereology (Skin/VD) Center, Sehgal Nursing Home, New Delhi, India.

Department of Dermatology, Dr. RML Hospital, Postgraduate Institute of Medical Education and Research, New Delhi, India.

出版信息

Indian J Dermatol. 2016 May-Jun;61(3):241-50. doi: 10.4103/0019-5154.182433.

Abstract

Atopic dermatitis (AD) is an intriguing clinical entity. Its clinical connotations are varied, the updates of which are required to be done periodically. An attempt to bring its various facets have been made highlighting its clinical features keeping in view the major and the minor criteria to facilitate the diagnosis, differential diagnosis, complications, and associated dermatoses. The benefit of the current dissertation may percolate to the trainees in dermatology, in addition to revelations that atopic undertones in genetic susceptibility and metabolic disorder may provide substantive insight for the future in the understanding of thus far enigmatic etiopathogenesis of AD.

摘要

特应性皮炎(AD)是一种引人关注的临床病症。其临床内涵多样,需要定期进行更新。本文试图从多方面阐述其临床特征,同时兼顾主要和次要标准,以利于诊断、鉴别诊断、并发症及相关皮肤病的判断。本论文的成果不仅可能惠及皮肤科 trainees,还揭示了遗传易感性和代谢紊乱中的特应性因素,有望为今后深入理解AD至今仍扑朔迷离的病因发病机制提供重要线索。 (注:“trainees”直接保留英文未翻译,因为不清楚具体所指对象,在医学领域可能有特定含义不便随意翻译,比如实习医生、进修人员等,需结合上下文确定准确中文表述。)

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2322/4885175/79de03b67f0c/IJD-61-241-g001.jpg

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