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三种不同手术方法治疗真性压力性尿失禁的比较:前瞻性随机研究

Comparison of three different surgical procedures for genuine stress incontinence: prospective randomized study.

作者信息

Bergman A, Ballard C A, Koonings P P

机构信息

Gynecology-Urology Division, Women's Hospital, Los Angeles County--University of Southern California Medical Center 90033.

出版信息

Am J Obstet Gynecol. 1989 May;160(5 Pt 1):1102-6. doi: 10.1016/0002-9378(89)90169-5.

DOI:10.1016/0002-9378(89)90169-5
PMID:2729386
Abstract

One hundred seven consecutive patients with clinical and urodynamic findings of genuine stress incontinence not previously treated were prospectively allocated in a randomized manner to one of three surgical procedures: anterior colporrhaphy, revised Pereyra procedure, or Burch retropubic urethropexy. Randomization included the surgical procedure and choice of surgeon (one of the three authors). Clinical and urodynamic evaluations were repeated at 3 months and 1 year after surgery. Differences in cure rates among the three procedures at the 3-month postoperative evaluation were insignificant (82%, 84%, and 92% for the anterior colporrhaphy, Pereyra, and Burch respectively) but became statistically significant at the 1 year postoperative evaluation (cure rates of 65%, 72%, and 91% for the anterior colporrhaphy, Pereyra, and Burch respectively, p less than 0.05). In our hands the Burch procedure stabilized the urethrovesical junction and prevented its descent during straining (evaluated by a postoperative Q-tip test) more effectively than either the Pereyra or anterior colporrhaphy. No procedure resulted in severe postoperative voiding difficulties. The present prospective randomized study demonstrates that in our hands the abdominal retropubic operation for genuine stress incontinence in patients not previously operated on results in a higher cure rate when compared with anterior colporrhaphy or Pereyra procedure.

摘要

107例此前未经治疗、有真性压力性尿失禁临床及尿动力学表现的连续患者被前瞻性随机分配至三种外科手术之一:前路阴道修补术、改良佩雷拉手术或伯奇耻骨后尿道悬吊术。随机分组包括手术方式及术者选择(三位作者之一)。术后3个月和1年重复进行临床及尿动力学评估。三种手术方式术后3个月评估时治愈率差异无统计学意义(前路阴道修补术、佩雷拉手术和伯奇手术的治愈率分别为82%、84%和92%),但术后1年评估时差异有统计学意义(前路阴道修补术、佩雷拉手术和伯奇手术的治愈率分别为65%、72%和91%,p<0.05)。在我们的操作中,伯奇手术比佩雷拉手术或前路阴道修补术更有效地稳定尿道膀胱连接部,并防止其在用力时下移(通过术后棉签试验评估)。没有一种手术导致严重的术后排尿困难。本前瞻性随机研究表明,在我们的操作中,对于此前未接受过手术的真性压力性尿失禁患者,耻骨后腹部手术与前路阴道修补术或佩雷拉手术相比,治愈率更高。

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