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化疗(美法仑)后急性白血病

Acute leukemia after chemotherapy (melphalan).

作者信息

Einhorn N

出版信息

Cancer. 1978 Feb;41(2):444-7. doi: 10.1002/1097-0142(197802)41:2<444::aid-cncr2820410210>3.0.co;2-8.

Abstract

During the years 1966-1973 474 patients with ovarian carcinoma were treated with melphalan. Of these, 48 patients received at least 300 mg melphalan and survived at least 3 years; four cases of acute leukemia were found among these 48 patients. All cases belonged to a group of 12 cases receiving 800 mg melphalan or more.

摘要

1966年至1973年间,474例卵巢癌患者接受了美法仑治疗。其中,48例患者接受了至少300毫克美法仑治疗且存活至少3年;在这48例患者中发现了4例急性白血病。所有病例均属于接受800毫克或更多美法仑治疗的12例患者组。

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