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晚期外耳道胆脂瘤患者病因及手术结果的重新审视

Reexamination of Etiology and Surgical Outcome in Patient With Advanced External Auditory Canal Cholesteatoma.

作者信息

Konishi Masaya, Iwai Hiroshi, Tomoda Koichi

机构信息

Department of Otolaryngology-Head and Neck Surgery, Kansai Medical University, Osaka, Japan.

出版信息

Otol Neurotol. 2016 Jul;37(6):728-34. doi: 10.1097/MAO.0000000000001079.

Abstract

OBJECTIVE

To describe the etiology of advanced cases of external auditory canal (EAC) cholesteatoma (EACC), and to report the surgical management and outcomes based on canalplasty depending on the extent of adjacent structures involvement around the EAC.

STUDY DESIGN

Retrospective case review.

SETTING

University hospital.

PATIENTS

Participants comprised 28 patients (12 males, 16 females) ranging in age from 9 to 86 years old. All patients presented with advanced-stage EACC (Naim's classification: stage III/IV).

INTERVENTION

Surgery ranged from simple bony meatoplasty with cartilage graft repair to more enlarged EAC canalplasty combined with tympanoplasty.

RESULT

EACC was categorized as idiopathic in 22 patients and secondary EACC in six patients. Six patients with idiopathic EACC were receiving hemodialysis, one of whom showed bilateral pathology. Particularly in cases with epithelial invasion into the hypotympanum immediately adjacent to the jugular bulb, multi-layered repair including bone paste, post-auricular pedicled musculo-periosteal flap, auto cartilage, and temporalis muscle fascia were required. Five patients required revision surgery (17%), including one case of recurrent (reconstructed) cholesteatoma and three cases of perforation of the tympanic membrane.

CONCLUSION

In the majority of our series, underlying diseases followed with microangiopathy and angiogenesis could be possible candidates in the etiology of EACC. Enlarged bony meatoplasty and multilayered reconstruction surgery brought about self-cleaning and dried the EAC in advanced-stage EACC.

摘要

目的

描述外耳道胆脂瘤(EACC)晚期病例的病因,并根据外耳道周围相邻结构受累程度报告基于外耳道成形术的手术治疗方法及结果。

研究设计

回顾性病例分析。

研究地点

大学医院。

患者

研究对象包括28例患者(12例男性,16例女性),年龄9至86岁。所有患者均为EACC晚期(奈姆分类:III/IV期)。

干预措施

手术范围从单纯的带软骨移植修复的骨性外耳道成形术到更广泛的外耳道成形术联合鼓室成形术。

结果

22例患者的EACC被归类为特发性,6例为继发性EACC。6例特发性EACC患者正在接受血液透析,其中1例为双侧病变。特别是在鼓膜下紧邻颈静脉球处有上皮侵犯的病例中,需要进行包括骨糊、耳后带蒂肌骨膜瓣、自体软骨和颞肌筋膜的多层修复。5例患者需要进行翻修手术(17%),包括1例复发性(重建后)胆脂瘤和3例鼓膜穿孔。

结论

在我们的大多数病例系列中,伴有微血管病变和血管生成的基础疾病可能是EACC病因的候选因素。扩大的骨性外耳道成形术和多层重建手术使晚期EACC的外耳道实现了自清洁和干燥。

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