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白塞病与妊娠——一例病例报告及文献综述

Behcet's disease and pregnancy-a case report and literature review.

作者信息

Xu Chuanlu, Bao Shihua

机构信息

Department of Obstetrics, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.

Department of Reproductive Immunology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.

出版信息

Am J Reprod Immunol. 2017 Jan;77(1). doi: 10.1111/aji.12530. Epub 2016 Jun 14.

Abstract

This case study reports on a rare case of a woman with Behcet's disease (BD), uterine malformation and antiphospholipid syndrome, who successfully delivered a baby without any complications during the perinatal period. The woman, who was diagnosed with BD with relapsing oral, ocular, and genital involvement 8 years ago, registered in our clinic with a history of two inevitable miscarriages. Laboratory findings were positive for anti-β -glycoprotein I antibodies (anti-β -GP-I). Three-dimensional ultrasound showed that her uterus was unicornuate, with only a normal left side. After treatment, the woman had a cesarean section for breech presentation of a healthy male infant weighing 2700 g. The postpartum period was uneventful. The possible effects of BD on pregnancy outcomes and how to manage BD patients are discussed with a review of the literature.

摘要

本病例报告了一名患有白塞病(BD)、子宫畸形和抗磷脂综合征的罕见女性病例,该女性在围产期成功分娩,未出现任何并发症。该女性8年前被诊断为复发性口腔、眼部和生殖器受累的白塞病,因有两次难免流产史前来我院就诊。实验室检查发现抗β-糖蛋白I抗体(抗β-GP-I)呈阳性。三维超声显示她的子宫为单角子宫,仅左侧正常。经过治疗,该女性因臀位剖宫产分娩出一名体重2700g的健康男婴。产后情况平稳。本文结合文献复习,讨论了白塞病对妊娠结局的可能影响以及如何管理白塞病患者。

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