Jonville-Béra Annie-Pierre, Mallaret Michel, Sgro Catherine
Centre régional de pharmacovigilance et d'information sur le médicament, service de pharmacologie, CHU de Tours, 2, boulevard Tonnellé, 37044 Tours cedex 9, France.
Centre régional de pharmacovigilance et d'information sur le médicament, CHU de Grenoble, 38043 Grenoble cedex 09, France.
Therapie. 2016 Sep;71(4):351-4. doi: 10.1016/j.therap.2016.05.002. Epub 2016 May 21.
In 1976, the Regional Pharmacovigilance Centres were created in France to collect and analyze adverse drug reactions. Even if they have, to date, managed and transmitted more than 583,000 adverse drug reactions to the French and international health authorities, the missions of these university hospital structures supervised by clinical pharmacologists are not limited to this activity. They also provide a consulting and diagnostic aid for drug diseases. Their other main mission is information about drugs and their proper use for health professionals and patients on any matter relating to medicines. These queries are used to adjust and focus the training of health professionals in prevention of drug risks and improvement of drug use. Beside signal detection and identification of alerts, the 31 Regional Pharmacovigilance Centres collaborate with the French Drug Agency (Agence nationale de sécurité du medicament et des produits de santé [ANSM]) by achieving expertise on drugs and participation in various working groups and committees. Finally, Regional Pharmacovigilance Centres participate in scientific advancement through research and publication activities.
1976年,法国设立了地区药物警戒中心,以收集和分析药品不良反应。尽管迄今为止,这些中心已向法国和国际卫生当局管理并传递了超过58.3万例药品不良反应,但这些由临床药理学家监督的大学医院机构的任务并不局限于此。它们还为药物疾病提供咨询和诊断援助。它们的另一项主要任务是就与药品有关的任何事项,向卫生专业人员和患者提供有关药品及其正确使用的信息。这些咨询用于调整和聚焦卫生专业人员在预防药物风险和改善药物使用方面的培训。除了信号检测和警报识别外,31个地区药物警戒中心还与法国药品管理局(法国国家药品和健康产品安全局[ANSM])合作,开展药品专业知识研究,并参与各种工作组和委员会。最后,地区药物警戒中心通过研究和出版活动参与科学进步。