Theitler J, Dassa D, Gelernter I, Gandelman-Marton R
Electroencephalography Laboratory, Assaf Harofeh Medical Center, Zerifin, Israel.
Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Eur J Neurol. 2016 Sep;23(9):1477-81. doi: 10.1111/ene.13065. Epub 2016 Jun 14.
The interictal electroencephalogram (EEG) has an important role in the classification and treatment of epilepsy. In busy EEG laboratories, valuable resources are used in order to comply with current recommendations regarding the length of EEG recordings. Our aim was to examine the time to first interictal epileptiform discharge (IED) in standard and sleep-deprived EEGs.
Standard and sleep-deprived EEG recordings with IEDs were retrospectively reviewed during a 2-year period. Bedside EEGs and long-term video-EEGs were excluded. IED latency according to EEG type, age group and inpatient/outpatient status was analyzed with the Kaplan-Meier estimator.
The study group included 684 patients, 372 (54%) males, aged 0.2-89 years. Standard (n = 316) and sleep-deprived (n = 368) EEGs were performed in 245 inpatients and 439 outpatients. The EEG was requested in 96% of the inpatients following a seizure. Most IEDs were recorded whilst the patients were awake (43%) or drowsy (34%). Ninety percent of the IEDs were recorded within 18.5 min, earlier in standard (14.6 vs. 21.3 min) (P = 0.024) EEGs and in inpatients (14 vs. 21.3 min) (P = 0.002). IED latency was unaffected by age.
Electroencephalogram type and admission status may be used for individual determination of the duration of EEG recording. Reducing the duration of standard and sleep-deprived EEGs may be considered especially in inpatients.
发作间期脑电图（EEG）在癫痫的分类和治疗中具有重要作用。在繁忙的脑电图实验室中，为了遵循当前关于脑电图记录时长的建议，会消耗宝贵的资源。我们的目的是研究标准脑电图和剥夺睡眠脑电图中首次发作间期癫痫样放电（IED）出现的时间。
回顾性分析了2年期间记录到IED的标准脑电图和剥夺睡眠脑电图。排除床边脑电图和长期视频脑电图。使用Kaplan-Meier估计器分析根据脑电图类型、年龄组和住院/门诊状态的IED潜伏期。
研究组包括684例患者，372例（54%）为男性，年龄0.2 - 89岁。对245例住院患者和439例门诊患者进行了标准脑电图（n = 316）和剥夺睡眠脑电图（n = 368）检查。96%的住院患者在发作后进行了脑电图检查。大多数IED是在患者清醒（43%）或困倦（34%）时记录到的。90%的IED在18.5分钟内记录到，在标准脑电图（14.6对21.3分钟）（P = 0.024）和住院患者（14对21.3分钟）（P = 0.002）中记录时间更早。IED潜伏期不受年龄影响。
脑电图类型和入院状态可用于个体化确定脑电图记录时长。尤其是对于住院患者，可考虑缩短标准脑电图和剥夺睡眠脑电图的时长。
