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阻生齿拔除术后不预防性使用抗生素的益处。

Benefits of not Prescribing Prophylactic Antibiotics After Third Molar Surgery.

作者信息

Prajapati Anchal, Prajapati Aalap, Sathaye Swati

机构信息

Department of Dental and Implant Surgery, Pramukh Swami Medical College and Hospital, Karamsad, Gujarat India ; 12/C Shivam Society Channi Jakat Naka, Vadodara, Gujarat India.

Department of Dental and Implant Surgery, Pramukh Swami Medical College and Hospital, Karamsad, Gujarat India.

出版信息

J Maxillofac Oral Surg. 2016 Jun;15(2):217-20. doi: 10.1007/s12663-015-0814-1. Epub 2015 Jul 5.

DOI:10.1007/s12663-015-0814-1
PMID:27298545
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4871824/
Abstract

AIM AND OBJECTIVE

The aim of the study is to reinstate the fact that antibiotics are not required as prophylaxis for third molar surgery. So the standard of care after extraction of mandibular third molar surgery for all healthy patients should be a good anti-inflammatory regimen rather than a antibiotic prophylaxis.

CONTEXT

Surgical removal of impacted mandibular third molar is the most common procedure and many complications are usually encountered in this procedure like-pain, trismus, infection, swelling, inflammation and nerve damage. Now, the question that arises is does the age old practice of prescribing postoperative antibiotics solve these problems or adds on some new. The data collected and analysed in our observational study, however, reinstates that instead, it is the proper aseptic precautions and good anti-inflammatory regimen that are more important than the prophylactic antibiotics (Pasupathy and Alexander in J Craniofac Surg, 2011). Moreover, giving antibiotics means opening up the loopholes to bacterial resistance.

SETTINGS AND DESIGN

A retrospective analysis of the data collected from 40 patients coming to the department of Dental and Implant Surgery, Karamsad, Anand between October 2014 and December 2014, operated for third molar surgery was carried out.

MATERIALS AND METHODS

Data from 40 patients requiring disimpaction of mandibular third molar was analysed. Postoperatively, only anti-inflammatory medication was prescribed to all the patients.

RESULTS

None of the patients showed any of the signs or symptoms of infection.

摘要

目的

本研究旨在重申一个事实,即下颌第三磨牙手术无需预防性使用抗生素。因此,对于所有健康患者,下颌第三磨牙拔除术后的护理标准应是良好的抗炎方案,而非抗生素预防。

背景

下颌阻生第三磨牙的外科拔除是最常见的手术,在此手术中通常会遇到许多并发症,如疼痛、牙关紧闭、感染、肿胀、炎症和神经损伤。现在出现的问题是,长期以来术后使用抗生素的做法能否解决这些问题,还是会带来一些新问题。然而,我们在观察性研究中收集和分析的数据重申,正确的无菌预防措施和良好的抗炎方案比预防性抗生素更重要(帕苏帕蒂和亚历山大,《颅面外科杂志》,2011年)。此外,使用抗生素意味着为细菌耐药性打开了漏洞。

设置与设计

对2014年10月至2014年12月期间到阿南德卡拉姆萨德牙科与种植牙外科就诊并接受第三磨牙手术的40例患者收集的数据进行回顾性分析。

材料与方法

分析40例需要拔除下颌第三磨牙患者的数据。术后,仅给所有患者开了抗炎药。

结果

所有患者均未出现任何感染的体征或症状。

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本文引用的文献

1
Efficacy of postoperative prophylactic antibiotic therapy in third molar surgery.第三磨牙手术中术后预防性抗生素治疗的疗效
J Clin Diagn Res. 2014 May;8(5):ZC14-6. doi: 10.7860/JCDR/2014/7441.4325. Epub 2014 May 15.
2
Antibiotic prophylaxis in third molar surgery: a review.第三磨牙手术中的抗生素预防:综述。
Oral Surg Oral Med Oral Pathol Oral Radiol. 2012 Dec;114(6):e5-12. doi: 10.1016/j.oooo.2011.10.023. Epub 2012 May 30.
3
Clinical and surgical evaluation of the indication of postoperative antibiotic prescription in third molar surgery.第三磨牙手术术后抗生素应用指征的临床和手术评估。
Oral Surg Oral Med Oral Pathol Oral Radiol. 2012 Nov;114(5 Suppl):S26-31. doi: 10.1016/j.tripleo.2011.08.018. Epub 2012 Jan 27.
4
Prophylaxis versus pre-emptive antibiotics in third molar surgery: a randomised control study.第三磨牙手术中预防性抗生素与先发制性抗生素的比较:一项随机对照研究。
Niger Postgrad Med J. 2011 Jun;18(2):105-10.
5
Antibiotic prophylaxis in third molar surgery.智齿拔除术中的抗生素预防
J Craniofac Surg. 2011 Mar;22(2):551-3. doi: 10.1097/SCS.0b013e31820745c7.
6
Antibiotic prophylaxis in third molar surgery: A randomized double-blind placebo-controlled clinical trial using split-mouth technique.第三磨牙手术中的抗生素预防:一项采用分口技术的随机双盲安慰剂对照临床试验。
Int J Oral Maxillofac Surg. 2010 Feb;39(2):107-14. doi: 10.1016/j.ijom.2009.12.014. Epub 2010 Feb 1.
7
Abuse of antibiotic prophylaxis in third molar surgeries.第三磨牙手术中抗生素预防的滥用。
J Oral Maxillofac Surg. 2009 Nov;67(11):2551-2. doi: 10.1016/j.joms.2009.06.020.
8
Effectiveness of antibiotic prophylaxis in third molar surgery: a meta-analysis of randomized controlled clinical trials.第三磨牙手术中抗生素预防性用药的有效性:一项随机对照临床试验的荟萃分析
J Oral Maxillofac Surg. 2007 Oct;65(10):1909-21. doi: 10.1016/j.joms.2007.03.004.
9
Efficacy of amoxicillin/clavulanic acid in preventing infectious and inflammatory complications following impacted mandibular third molar extraction.阿莫西林/克拉维酸预防下颌阻生第三磨牙拔除术后感染性及炎性并发症的疗效
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005 Jul;100(1):e11-8. doi: 10.1016/j.tripleo.2005.03.025.
10
Postoperative prophylactic antibiotic treatment in third molar surgery--a necessity?第三磨牙手术中的术后预防性抗生素治疗——有必要吗?
J Oral Maxillofac Surg. 2004 Jan;62(1):3-8; discussion 9. doi: 10.1016/j.joms.2003.05.004.