Wilson W B, Leavengood J M, Ringel S P, Bott A D
Department of Ophthalmology, University of Colorado Health Sciences Center, Denver.
Ann Neurol. 1989 Mar;25(3):286-90. doi: 10.1002/ana.410250313.
While sudden monocular blindness and occlusion of the central retinal artery associated with acute thrombosis of the internal carotid artery are well reported, concurrent unilateral ophthalmoparesis is not. We studied 3 adult men who did not have other major signs of vascular disease but who exhibited the complete syndrome. The initial paresis of the oculomotor, trochlear, and abducens nerves varied in each individual and slowly cleared over days to weeks in all, but vision did not return in any. Each had mild-to-moderate signs of hemispheric dysfunction. In each, the thrombus extended from the origin of the internal carotid to its intracranial bifurcation into the anterior and middle cerebral arteries. It also occluded the proximal one-half to two-thirds of the ophthalmic artery. None had evidence of vasculitis or compromise of the posterior circulation.
虽然突发性单眼失明以及与颈内动脉急性血栓形成相关的视网膜中央动脉阻塞已有大量报道,但并发单侧眼肌麻痹的情况却未见报道。我们研究了3名成年男性,他们没有其他主要血管疾病体征,但表现出了完整的综合征。动眼神经、滑车神经和展神经的初始麻痹在每个个体中各不相同,且在所有人中均在数天至数周内缓慢消退,但视力均未恢复。每个人都有轻度至中度的半球功能障碍体征。每个人的血栓均从颈内动脉起始处延伸至其颅内分支为大脑前动脉和大脑中动脉处。它还阻塞了眼动脉近端的二分之一至三分之二。没有人有血管炎或后循环受损的证据。