Amsbaugh Mark J, Bertke Matthew, Cheerva Alexandra, Silverman Craig, Dunlap Neal
Departments of *Radiation Oncology †Pediatrics, University of Louisville, Louisville, KY.
J Pediatr Hematol Oncol. 2016 Aug;38(6):e199-201. doi: 10.1097/MPH.0000000000000617.
Stereotactic ablative radiotherapy delivers a high dose of radiation to a small volume over several fractions. Although most commonly used as a treatment alternative to surgery in adult patients with primary lung cancer, its use has now been reported in children with metastatic disease to the lungs. We present the case of a child treated with stereotactic ablative radiotherapy to pulmonary metastases in preparation for a salvage stem cell transplant. The patient was treated to a dominant pulmonary nodule and successfully received his stem cell transplant, however he developed clinical and radiographic findings consistent with pneumonitis several months after treatment.
立体定向消融放疗在多个分次中向小体积区域给予高剂量辐射。虽然它最常用于成年原发性肺癌患者作为手术的替代治疗方法,但目前已有报道称其用于肺部转移疾病的儿童患者。我们报告了一例接受立体定向消融放疗治疗肺部转移灶以准备挽救性干细胞移植的儿童病例。该患者接受了对一个主要肺结节的治疗,并成功接受了干细胞移植,然而在治疗后几个月,他出现了与肺炎一致的临床和影像学表现。