Malter M, Fink G R
Fortschr Neurol Psychiatr. 2016 May;84(5):281-8. doi: 10.1055/s-0042-106388. Epub 2016 Jun 14.
The identification of an antibody-associated autoimmune encephalitis underlying diverse syndromes, typically comprising epileptic seizures and neuropsychiatric symptoms, and their favorable prognosis, when treated with immunotherapies, is one of the success stories in neurology in recent years. Here we review current widely used therapy regimens in antibody-associated autoimmune encephalitis and the prognosis of the different antibody-associated sub-forms. The main therapeutic instruments encompass tumor therapy (if tumor is detected) and immunotherapies, though recommendations are mainly based on retrospective data analysis. The primary therapeutic goal is complete remission. The degree to which this can be accomplished depends upon the different sub-forms.
一种与抗体相关的自身免疫性脑炎被确定为多种综合征的基础，这些综合征通常包括癫痫发作和神经精神症状，并且在接受免疫治疗时预后良好，这是近年来神经学领域的成功案例之一。在此，我们回顾了目前在与抗体相关的自身免疫性脑炎中广泛使用的治疗方案以及不同抗体相关亚型的预后情况。主要治疗手段包括肿瘤治疗（如果检测到肿瘤）和免疫治疗，不过相关建议主要基于回顾性数据分析。主要治疗目标是完全缓解。能够实现这一目标的程度取决于不同的亚型。
