与IgG4相关疾病相关的多发性冠状动脉瘤和胸主动脉炎
Multiple Coronary Artery Aneurysms and Thoracic Aortitis Associated with IgG4-related Disease.
作者信息
Nishimura Shunsuke, Amano Masashi, Izumi Chisato, Kuroda Maiko, Yoshikawa Yusuke, Takahashi Yusuke, Imamura Sari, Onishi Naoaki, Tamaki Yodo, Enomoto Soichiro, Miyake Makoto, Tamura Toshihiro, Kondo Hirokazu, Kaitani Kazuaki, Nakagawa Yoshihisa
机构信息
Department of Cardiology, Tenri Hospital, Japan.
出版信息
Intern Med. 2016;55(12):1605-9. doi: 10.2169/internalmedicine.55.6314. Epub 2016 Jun 15.
A 60-year-old man was admitted due to the onset of right coronary artery (RCA) aneurysms. Coronary angiography showed two RCA aneurysms and focal stenosis with limitations in the blood flow. Balloon angioplasty was performed. However, the follow-up coronary angiography showed restenosis, an enlarged proximal aneurysm and a newly formed aneurysm. The serum immunoglobulin G4 level was elevated to 1,350 mg/dL and fluorodeoxyglucose positron emission tomography showed increased uptake in the ascending aorta, so the patient was diagnosed with immunoglobulin G4-related vascular disease. The prevention of further enlargement of the aneurysms and an improvement in the RCA flow were achieved with steroid therapy. Steroid therapy may therefore be effective for immunoglobulin G4-related vascular disease.
一名60岁男性因右冠状动脉（RCA）动脉瘤发作入院。冠状动脉造影显示两个RCA动脉瘤以及血流受限的局灶性狭窄。进行了球囊血管成形术。然而，随访冠状动脉造影显示有再狭窄、近端动脉瘤增大以及新形成的动脉瘤。血清免疫球蛋白G4水平升高至1350mg/dL，氟脱氧葡萄糖正电子发射断层扫描显示升主动脉摄取增加，因此该患者被诊断为免疫球蛋白G4相关血管疾病。通过类固醇治疗实现了预防动脉瘤进一步扩大以及改善RCA血流。因此，类固醇治疗可能对免疫球蛋白G4相关血管疾病有效。
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