Segev S, Barzilai A, Rosen N, Joseph G, Rubinstein E
Infectious Diseases Unit, Chaim Sheba Medical Center, Tel-Aviv University Medical School, Tel-Hashomer, Israel.
Arch Intern Med. 1989 Jun;149(6):1314-6.
Ten patients with acute meningitis caused by gram-negative bacteria were treated with pefloxacin intravenously for a mean period of 10 days. Eight patients responded clinically to pefloxacin treatment, and the causative organisms were eradicated from the cerebrospinal fluid in 9 of the 10 patients. Pefloxacin may offer a new, efficacious, and safe therapy for gram-negative meningitis.
10例由革兰氏阴性菌引起的急性脑膜炎患者接受了培氟沙星静脉治疗，平均疗程为10天。8例患者对培氟沙星治疗有临床反应，10例患者中有9例脑脊液中的致病微生物被清除。培氟沙星可能为革兰氏阴性菌脑膜炎提供一种新的、有效且安全的治疗方法。
