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Tumor inhibiting properties of stereoisomeric [1,2-bis(3-hydroxyphenyl)ethylenediamine]dichloroplatinum(II)-compl exe s, Part I: Synthesis.

作者信息

Jennerwein M, Gust R, Müller R, Schönenberger H, Engel J, Berger M R, Schmähl D, Seeber S, Osieka R, Atassi G

出版信息

Arch Pharm (Weinheim). 1989 Jan;322(1):25-9. doi: 10.1002/ardp.19893220107.

DOI:10.1002/ardp.19893220107
PMID:2730286
Abstract

The synthesis of the stereoisomeric 1,2-bis(3-hydroxyphenyl)ethylenediamines (1-4) from meso-1,2-bis(2-hydroxyphenyl)ethylenediamine and 3-methoxybenzaldehyde by a diaza-Cope-rearrangement and subsequent ether cleavage with BBr3 and their conversion into the [1,2-bis(3-hydroxyphenyl)ethylenediamine]dichloroplatinum(II)-complexes with K2PtCl4 (1-PtCl2 - 4-PtCl2) is described.

摘要

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引用本文的文献

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