Pauloski Barbara R, Nasir Sazzad M
Department of Communication Sciences and Disorders, University of Wisconsin-Milwaukee, Wisconsin
Department of Communication Sciences and Disorders, Northwestern University, Illinois.
Physiol Rep. 2016 Jun;4(11). doi: 10.14814/phy2.12752.
Pharyngeal delay is a significant swallowing disorder often resulting in aspiration. It is suspected that pharyngeal delay originates from sensory impairment, but a direct demonstration of a link between oral sensation and pharyngeal delay is lacking. In this study involving six patients with complaints of dysphagia, taste sensation of the oral tongue was measured and subsequently related to swallowing kinematics. It was found that a response bias for sour taste was significantly correlated with pharyngeal delay time on paste, highlighting oral sensory contributions to swallow motor dysfunctions. Investigating the precise nature of such a link between oral sensation and dysphagia would constitute a basis for understanding the disorder. The results of this study highlight oral sensory contributions to pharyngeal swallow events and provide impetus to examine this link in larger samples of dysphagic patients.
咽期延迟是一种严重的吞咽障碍，常导致误吸。人们怀疑咽期延迟源于感觉障碍，但缺乏口腔感觉与咽期延迟之间联系的直接证据。在这项针对六名有吞咽困难主诉患者的研究中，测量了口腔舌部的味觉，并将其与吞咽运动学相关联。结果发现，对酸味的反应偏差与糊状食物的咽期延迟时间显著相关，突出了口腔感觉对吞咽运动功能障碍的影响。研究口腔感觉与吞咽困难之间这种联系的确切性质将为理解该障碍奠定基础。本研究结果突出了口腔感觉对咽期吞咽事件的影响，并为在更大样本的吞咽困难患者中研究这种联系提供了动力。
