静脉注射和口服后犬体内氯化阿伯农的药代动力学
Pharmacokinetics of ambenonium chloride in dogs after intravenous and oral administration.
作者信息
Tharasse-Bloch C, Chabenat C, Boucly P, Boismare F, Marchand J
机构信息
Laboratoire de Pharmacochimie, U.E.R. de Médecine-Pharmacie de Rouen, St. Etienne du Rouvray, France.
出版信息
Arzneimittelforschung. 1989 Feb;39(2):257-8.
PMID:2730696
Abstract
Plasma concentrations of ambenonium chloride (Mytélase) were studied, using a high pressure liquid chromatographic technique, in 11 dogs, after intravenous or oral administration of the drug. The results found suggest a complex multi-compartment storage with several periodical releases in general circulation.
摘要
采用高压液相色谱技术，对11只犬静脉注射或口服氯化阿伯农（酶抑宁）后的血浆浓度进行了研究。研究结果表明，该药在体循环中呈现复杂的多室储存及多次周期性释放。
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