Benzalim Ahmed, Auhmani Aziz, Ait Itto My Youssef, Daran Jean-Claude, Abdelwahed Auhmani
Laboratoire de Physico-Chimie Moléculaire et Synthèse Organique, Département de Chimie, Faculté des Sciences, Semlalia BP 2390, Marrakech 40001, Morocco.
Laboratoire de Chimie de Coordination, CNRS UPR8241, 205 route de Narbonne, 31077 Toulouse Cedex 04, France.
Acta Crystallogr E Crystallogr Commun. 2016 Apr 15;72(Pt 5):709-11. doi: 10.1107/S2056989016006174. eCollection 2016 May 1.
The asymmetric unit of the title compound, C16H24Cl2O2, contains two independent mol-ecules (A and B) which are built from three fused rings, viz. a seven-membered heptane ring, a six-membered cyclo-hexyl ring bearing a ketone and an alcohol group, and a cyclo-propane ring bearing two Cl atoms. In the crystal, the two mol-ecules are linked via two O-H⋯O hydrogen bonds, forming an A-B dimer with an R 2 (2)(10) ring motif. The A mol-ecules of these dimers are linked via a C-H⋯O hydrogen bond, forming chains propagating along the a-axis direction. Both mol-ecules have the same absolute configuration, i.e. 1S,3R,8R,10S, which is based on the synthetic pathway and further confirmed by resonant scattering [Flack parameter = 0.03 (5)].
标题化合物C₁₆H₂₄Cl₂O₂的不对称单元包含两个独立的分子（A和B），它们由三个稠合环构成，即一个七元庚烷环、一个带有酮基和醇基的六元环己基环，以及一个带有两个氯原子的环丙烷环。在晶体中，这两个分子通过两个O—H⋯O氢键相连，形成具有R²(2)(10)环模式的A—B二聚体。这些二聚体的A分子通过C—H⋯O氢键相连，形成沿a轴方向延伸的链。两个分子具有相同的绝对构型，即1S,3R,8R,10S，这是基于合成途径并通过共振散射进一步确认的[Flack参数 = 0.03 (5)]。
