Best C J, Ewart M, Sumner E
Department of Anaesthesia, Hospital for Sick Children, London.
Br J Anaesth. 1989 May;62(5):576-7. doi: 10.1093/bja/62.5.576.
We describe two patients in whom rapid administration of vancomycin caused severe hypotension. Possible mechanisms for this effect are discussed, with reference to the role of the anaesthetist as administrator of drugs prescribed by others. Recommendations are made on safe administration of vancomycin with respect to rate of infusion and possible interactions.
我们描述了两名患者,他们在快速输注万古霉素后出现了严重低血压。本文讨论了导致这种效应的可能机制,并提及麻醉医生作为他人所开药物的给药者所起的作用。针对万古霉素的安全给药,就输注速度及可能的相互作用提出了建议。