类风湿性关节炎患者与健康成年人谷胱甘肽还原酶和谷胱甘肽过氧化物酶活性的比较。
A comparison of glutathione reductase and glutathione peroxidase activities in patients with rheumatoid arthritis and healthy adults.
作者信息
Braven J, Ansari N, Figgitt D P, Fisher A, Luders C, Hickling P, Whittaker M
机构信息
Department of Environmental Sciences, Plymouth Polytechnic, Devon, UK.
出版信息
Br J Rheumatol. 1989 Jun;28(3):212-5. doi: 10.1093/rheumatology/28.3.212.
A 30% increase in erythrocyte glutathione peroxidase (GP) activity was found in patients with rheumatoid arthritis when compared with healthy controls (p = 0.001) whereas the increase in glutathione reductase (GR) was statistically insignificant. No correlation was found between the activities of the enzymes and the erythrocyte sedimentation rate (ESR). The enzyme activities were independent of age, sex, or type of drug treatment of the patients. A possible interpretation of the results is presented.
与健康对照组相比，类风湿性关节炎患者的红细胞谷胱甘肽过氧化物酶（GP）活性增加了30%（p = 0.001），而谷胱甘肽还原酶（GR）的增加在统计学上不显著。未发现酶活性与红细胞沉降率（ESR）之间存在相关性。酶活性与患者的年龄、性别或药物治疗类型无关。文中给出了对这些结果的一种可能解释。
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