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心脏手术后患者的术后并发症。

Postoperative complications of patients undergoing cardiac surgery.

机构信息

Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy.

出版信息

Curr Opin Crit Care. 2016 Aug;22(4):386-92. doi: 10.1097/MCC.0000000000000319.

Abstract

PURPOSE OF REVIEW

Cardiac surgery is at high risk for the development of postoperative complications involving cardiovascular and respiratory system, as well as kidneys and central nervous system. The aim of this review is to provide an overview on the most recent findings concerning the type and incidence of different complications after cardiac surgery and to summarize the current recommendations.

RECENT FINDINGS

Despite an improvement of surgical and anaesthesia techniques that resulted in a significant decrease in mortality, postoperative complications play a major role in affecting morbidity, mortality, length of hospital stay and patients' quality of life. The most recent evidence suggests that fluid and inotropes administration should be targeted to maintain a cardiac index above 3 l/min/m throughout the perioperative period. Volatile anaesthesia and mechanical ventilation with low tidal volumes, low driving pressure and moderate-low positive end-expiratory pressure should be preferred. Preoperative steroids could reduce postoperative atrial fibrillation, whereas no drug has shown to effectively prevent kidney injury.

SUMMARY

Cardiac surgery is still at high risk for postoperative complications. The optimal type of anaesthesia, protective mechanical ventilation during and after surgery as well as haemodynamic management with vasoactive and inotropic drugs is still to be determined.

摘要

目的综述

心脏手术有发生心血管和呼吸系统、肾脏和中枢神经系统并发症的高风险。本文旨在概述心脏手术后不同并发症的类型和发生率的最新发现,并总结当前的建议。

最新发现

尽管外科和麻醉技术的改进显著降低了死亡率,但术后并发症在影响发病率、死亡率、住院时间和患者生活质量方面仍起着重要作用。最近的证据表明,应通过液体和正性肌力药物输注将心脏指数维持在整个围手术期的 3 l/min/m 以上。应优选使用挥发性麻醉和低潮气量、低驱动压和中低水平呼气末正压的机械通气。术前使用类固醇可减少术后心房颤动,但尚无药物可有效预防肾损伤。

总结

心脏手术后仍有发生并发症的高风险。最佳的麻醉类型、手术期间和之后的保护性机械通气以及血管活性和正性肌力药物的血流动力学管理仍有待确定。

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