Dickinson I K, Pryor J P
St Peter's Hospital, London.
Br J Urol. 1989 May;63(5):539-45. doi: 10.1111/j.1464-410x.1989.tb05953.x.
The papaverine test has become established in the investigation of impotence. Although a full response to papaverine excludes a significant vascular lesion, failure to respond may be due to either arterial deficiency or venous leakage. Pharmacocavernometry, which combines the papaverine test and an artificial erection test, was performed in 126 patients. Intracorporeal pressure was monitored following the intracorporeal injection of 80 mg papaverine; 10 min later, saline was infused to determine the presence of a venous leak. Five different responses were observed. Patients with a Type 1 or 2 response were psychogenic or neurogenic. Patients with a Type 3 response were arteriogenic and patients with a Type 4 or 5 response had significant venous leakage. The modified papaverine test permits more information to be gained concerning the aetiology of the impotence.
罂粟碱试验已被确立用于阳痿的检查。虽然对罂粟碱的充分反应可排除严重的血管病变，但无反应可能是由于动脉供血不足或静脉漏血。对126例患者进行了结合罂粟碱试验和人工勃起试验的药物海绵体测压。在海绵体内注射80毫克罂粟碱后监测海绵体内压力；10分钟后，注入生理盐水以确定是否存在静脉漏血。观察到五种不同的反应。1型或2型反应的患者为精神性或神经性。3型反应的患者为动脉性，4型或5型反应的患者有明显的静脉漏血。改良的罂粟碱试验能获得更多有关阳痿病因的信息。
