Han Zhaoyu, Yang Baokui, Yang Zhen, Xi Yumeng
College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, Jiangsu, China.
Anim Sci J. 2017 Feb;88(2):286-293. doi: 10.1111/asj.12648. Epub 2016 Jun 16.
Twenty-four Chinese Holstein growing steers were randomly divided into three groups and fed a diet containing 0 (the control group), 15 (treatment I group, or TG1) or 25 (treatment II group, or TG2) g/day 2-hydroxy-4-(methylthio) butanoic acid isopropyl ester (HMBi). Compared with the control group, the final body weights, total gains and average daily gains in the treatment groups increased (P < 0.01). The concentration of total protein (TP) for TG1 increased (P < 0.01). The levels of albumin in TG1 were higher than those in TG2 and the control group (P < 0.05). The concentration of alanine aminotransferase (ALT) in TG2 increased (P < 0.05), but concentrations of aspartate aminotransferase (AST) in the treatment groups decreased (P < 0.05). HMBi improved the concentrations of selenium in both TG1 (P < 0.05) and TG2 (P < 0.01). The levels of glutathion peroxidase (GSH-Px) in TG2 were higher than those of the control group (P < 0.05). Moreover, HMBi increased the concentrations of growth hormone (GH) in both TG1 (P < 0.05) and TG2 (P < 0.01). These results indicate that the addition of HMBi increases growth performance, serum concentrations of GH and AST; 15 g/day HMBi increases concentrations of total protein and albumin, and 25 g/day HMBi increases concentrations of ALT and GSH-Px.
将24头中国荷斯坦生长公牛随机分为三组，分别饲喂含0（对照组）、15（处理I组，即TG1）或25（处理II组，即TG2）克/天2-羟基-4-（甲硫基）丁酸异丙酯（HMBi）的日粮。与对照组相比，处理组的末体重、总增重和平均日增重均有所增加（P < 0.01）。TG1组的总蛋白（TP）浓度升高（P < 0.01）。TG1组的白蛋白水平高于TG2组和对照组（P < 0.05）。TG2组的丙氨酸氨基转移酶（ALT）浓度升高（P < 0.05），但处理组的天冬氨酸氨基转移酶（AST）浓度降低（P < 0.05）。HMBi提高了TG1组（P < 0.05）和TG2组（P < 0.01）的硒浓度。TG2组的谷胱甘肽过氧化物酶（GSH-Px）水平高于对照组（P < 0.05）。此外，HMBi提高了TG1组（P < 0.05）和TG2组（P < 0.01）的生长激素（GH）浓度。这些结果表明，添加HMBi可提高生长性能、血清GH和AST浓度；每天添加15克HMBi可提高总蛋白和白蛋白浓度，每天添加25克HMBi可提高ALT和GSH-Px浓度。
