糖尿病中的周围神经高分辨率超声
Peripheral nerve high-resolution ultrasound in diabetes.
作者信息
Breiner Ari, Qrimli Mohammad, Ebadi Hamid, Alabdali Majed, Lovblom Leif E, Abraham Alon, Albulahi Hana, Perkins Bruce A, Bril Vera
机构信息
Ellen and Martin Prosserman Centre for Neuromuscular Diseases, Department of Medicine, 5EC-309, Toronto General Hospital, University Health Network, 200 Elizabeth Street, Toronto, Ontario, M5G 2C4, Canada.
King Fahad Hospital, Ministry of Health, Madina, Saudi Arabia.
出版信息
Muscle Nerve. 2017 Feb;55(2):171-178. doi: 10.1002/mus.25223. Epub 2016 Nov 10.
INTRODUCTION
High-resolution ultrasound (HRU) is used in the diagnosis of peripheral neuropathies. There are conflicting data regarding HRU findings in patients with diabetic sensorimotor polyneuropathy (DSP). Our purpose in this study was to measure nerve cross-sectional areas (CSAs) in patients with diabetes, with and without DSP.
METHODS
We performed a prospective peripheral nerve HRU study of 100 diabetic subjects, assessed the CSA at predefined sites, and compared the results with those of 100 normal subjects. We evaluated the use of individual CSA values and various summary scores for diagnosis of DSP.
RESULTS
Diabetic subjects had higher CSA values than healthy volunteers, and those with DSP had higher CSA values. Three or more enlarged CSA sites predicted DSP with 64% sensitivity and 77% specificity.
CONCLUSIONS
Peripheral nerves are enlarged diffusely in diabetic patients, including sites not susceptible to bony compression. The number of enlarged CSA values can help predict the presence of DSP. Muscle Nerve, 2016 Muscle Nerve 55: 171-178, 2017.
引言
高分辨率超声（HRU）用于诊断周围神经病变。关于糖尿病感觉运动性多发性神经病变（DSP）患者的HRU检查结果，存在相互矛盾的数据。本研究的目的是测量患有和未患有DSP的糖尿病患者的神经横截面积（CSA）。
方法
我们对100名糖尿病受试者进行了一项前瞻性周围神经HRU研究，在预定义部位评估CSA，并将结果与100名正常受试者的结果进行比较。我们评估了使用个体CSA值和各种汇总评分来诊断DSP的情况。
结果
糖尿病受试者的CSA值高于健康志愿者，患有DSP的受试者CSA值更高。三个或更多CSA增大的部位预测DSP的敏感性为64%，特异性为77%。
结论
糖尿病患者的周围神经弥漫性增粗，包括不易受骨质压迫的部位。CSA增大值的数量有助于预测DSP的存在。《肌肉与神经》，2016年 2017年《肌肉与神经》55: 171 - 178
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