Kiratli Hayyam, Uzun Salih, Varan Ali, Akyüz Canan, Orhan Diclehan
Hacettepe University School of Medicine, Sihhiye, Ankara, Turkey.
Hacettepe University School of Medicine, Sihhiye, Ankara, Turkey.
J AAPOS. 2016 Jun;20(3):260-3. doi: 10.1016/j.jaapos.2016.01.009.
Inflammatory myofibroblastic tumor (IMT) is a distinct mesenchymal neoplasm of myofibroblastic spindle cells associated with an inflammatory infiltrate formed by lymphocytes, eosinophils, and plasma cells in a myxoid or collagenous stroma. This tumor has a predilection for children and young adults and most commonly occurs in the lungs, retroperitoneum, abdomen, and pelvis. Ocular and orbital involvement is exceedingly rare. We describe a case of IMT in a 7-year-old girl involving the cornea, conjunctiva, and the anterior orbit treated with crizotinib, resulting in complete tumor remission.
炎性肌纤维母细胞瘤（IMT）是一种独特的肌纤维母细胞性梭形细胞间叶性肿瘤，伴有淋巴细胞、嗜酸性粒细胞和浆细胞在黏液样或胶原性基质中形成的炎性浸润。该肿瘤好发于儿童和年轻人，最常见于肺部、腹膜后、腹部和骨盆。眼部和眼眶受累极为罕见。我们描述了一例7岁女孩的IMT，累及角膜、结膜和前眼眶，经克唑替尼治疗后肿瘤完全缓解。
