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非典型下颌肿胀致骨肉瘤误诊为成牙骨质细胞瘤:一例报告

Misdiagnosis of osteosarcoma as cementoblastoma from an atypical mandibular swelling: A case report.

作者信息

Fang Zao, Jin Shufang, Zhang Chenping, Wang Lizhen, He Yue

机构信息

Department of Oral Maxillofacial Head and Neck Oncology, Faculty of Oral and Maxillofacial Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai 200011, P.R. China.

Department of Oral Pathology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai 200011, P.R. China.

出版信息

Oncol Lett. 2016 Jun;11(6):3761-3765. doi: 10.3892/ol.2016.4433. Epub 2016 Apr 13.

Abstract

Cementoblastoma is a form of benign odontogenic tumor, with the preferred treatment consisting of tooth extraction and follow-up examinations, while in certain cases, follow-up examinations without surgery are performed. Osteosarcoma of the jaw is a rare, malignant, mesenchymal tumor, associated with a high mortality rate and low incidence of metastasis. Cementoblastoma and osteosarcoma of the jaw are dissimilar in terms of their histological type and prognosis; however, there are a number of covert associations between them. The present study describes the case of a 20-year-old female with an unusual swelling in the left mandible that had been present for 2 years. The patient was initially clinically diagnosed with cementoblastoma; however, following pathological examination, a diagnosis of osteosarcoma was confirmed. A total mandibulectomy was performed on the left mandible, with a fibular osteomyocutaneous flap used for reconstruction. At the 6-month post-operative examination, the patient demonstrated normal occlusion and oral commissure, and no recurrence or metastasis was observed over 2 years of follow-up.

摘要

成牙骨质细胞瘤是一种良性牙源性肿瘤,其首选治疗方法包括拔牙和后续检查,而在某些情况下,也会在不进行手术的情况下进行后续检查。颌骨骨肉瘤是一种罕见的恶性间叶性肿瘤,死亡率高且转移发生率低。成牙骨质细胞瘤和颌骨骨肉瘤在组织学类型和预后方面有所不同;然而,它们之间存在一些隐性关联。本研究描述了一名20岁女性的病例,其左下颌出现异常肿胀已达2年。患者最初临床诊断为成牙骨质细胞瘤;然而,经过病理检查,确诊为骨肉瘤。对左下颌进行了全下颌骨切除术,并使用腓骨骨肌皮瓣进行重建。术后6个月检查时,患者咬合和口角正常,随访2年未观察到复发或转移。

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