Weigl Paul, Strangio Antonio
Eur J Oral Implantol. 2016;9 Suppl 1:S89-106.
The purpose of this literature review is to systematically evaluate the impact of immediate implant placement and restoration (IIPR) on hard and soft tissues and to identify clinical parameters which influence the outcome.
An electronic search of the PubMed database was performed from January 2000 to September 2015. A further hand search was conducted in selected journals and only abstracts published in English were considered for review. Human clinical trials with at least 10 participants and which reported hard and soft tissue outcomes were assessed. Randomised controlled trials (RCT), prospective, prospective comparative and retrospective studies were considered. The effects of the following clinical parameters on hard and soft tissue outcomes were analysed: type of implant, primary stability, gingival biotype, flapless surgery, tooth extraction, spatial arrangement of the implant, socket grafting, the gap between implant surface and alveolar wall and the loading protocol.
17 studies (four RCT, six prospective, two comparative prospective, three controlled cohort and two retrospective studies) were included with 626 censored IIPR in 609 patients. A total of 411(65.56 %) implants were placed flapless vs 215 implants after raising a mucoperiosteal flap. Five studies defined raising a mucoperiostal flap as a mandatory part of the surgical protocol. The mean of the remaining gap in between the implant surface and the alveolar wall, the so-called "jump space", was reported for 170 implants ranging from 1.38 mm to 2.25 mm. Two hundred and one implant sites were not grafted, 405 were grafted, mostly with bone substitutes; for 20 no information was available. For 419 implants, a minimum insertion torque of ≥ 32 Ncm or an ISQ value of ≥ 60 was reached; for 53 implants an insertion torque of 25 Ncm was accepted. The implants were mostly placed palatinally of the jaw bone. The vertical position of the platform was reported either to be 0.5 to 1.0 mm below the vestibular bone crest or 3 to 4 mm apical to the adjacent cementoenamel junction of the neighbouring tooth. Post-insertion healing with a non-functional occlusion occurred for 97.8% of the implants. The final single crowns were inserted 3 to 6 months after implant placement. The IIPR resulted in a high success (97.96 %) and survival rate (98.25%) after a mean followup period of 31.2 months. The soft-tissue biotype was evaluated in 379 (60.5%) sites as thick. The mean crestal bone and the mean interproximal mucosa level changes were less than 1 mm compared to the baseline. The midfacial periimplant mucosal level change was less than 0.95 mm. This level was reached for both thin and thick soft-tissue biotypes, without a significant difference. Only in one study did the thin biotypes show a significantly higher recession.
The systematic review revealed promising results for immediately placed and immediately restored implants (IIPR) in the anterior maxilla. The possible options of flapless surgery and absence of grafting of the socket allows a minimal surgical intervention. However, a strict patient selection seemed mandatory for all included clinical trials.
本综述的目的是系统评估即刻种植与修复(IIPR)对软硬组织的影响,并确定影响其结果的临床参数。
对2000年1月至2015年9月的PubMed数据库进行电子检索。在选定的期刊中进行了进一步的手工检索,仅纳入英文发表的摘要进行综述。评估了至少有10名参与者且报告了软硬组织结果的人体临床试验。纳入随机对照试验(RCT)、前瞻性、前瞻性比较和回顾性研究。分析了以下临床参数对软硬组织结果的影响:种植体类型、初期稳定性、牙龈生物型、不翻瓣手术、拔牙、种植体的空间排列、牙槽窝植骨、种植体表面与牙槽壁之间的间隙以及加载方案。
纳入17项研究(4项RCT、6项前瞻性、2项比较前瞻性、3项对照队列和2项回顾性研究),涉及609例患者的626颗经审查的IIPR。共411颗(65.56%)种植体采用不翻瓣植入,215颗种植体在掀起粘骨膜瓣后植入。5项研究将掀起粘骨膜瓣定义为手术方案的必要部分。报道了170颗种植体的种植体表面与牙槽壁之间的剩余间隙(即所谓的“跳跃间隙”)的平均值,范围为1.38mm至2.25mm。201个种植位点未植骨,405个种植位点植骨,大多使用骨替代物;20个种植位点无相关信息。419颗种植体达到了≥32Ncm的最小插入扭矩或≥60的ISQ值;53颗种植体接受了25Ncm的插入扭矩。种植体大多植入颌骨的腭侧。种植体平台的垂直位置据报道要么位于前庭骨嵴下方0.5至1.0mm,要么位于相邻牙齿邻面牙骨质釉质界根尖3至4mm处。97.8%的种植体在植入后采用无功能咬合进行愈合。最终单冠在种植体植入后3至6个月插入。在平均31.2个月的随访期后,IIPR取得了较高的成功率(97.96%)和存留率(98.25%)。在379个(60.5%)位点评估软组织生物型为厚型。与基线相比,平均嵴顶骨和平均邻间黏膜水平变化小于1mm。种植体周围面部中部黏膜水平变化小于0.95mm。薄型和厚型软组织生物型均达到此水平,无显著差异。仅在一项研究中,薄型生物型显示出明显更高的退缩。
系统评价显示,上颌前部即刻种植与即刻修复(IIPR)取得了令人满意的结果。不翻瓣手术和牙槽窝不植骨的可能选择使得手术干预最小化。然而,对于所有纳入的临床试验,严格的患者选择似乎是必要的。