Trujillo H, Harry N, Arango A, Benítez G, Restrepo F, Mejía G I, Castrillón A L
Corporación para Investigaciones Biológicas, Medellin, Colombia.
Chemotherapy. 1989;35 Suppl 1:25-30. doi: 10.1159/000238717.
Aztreonam was administered to 20 children diagnosed as having any of the following infections: urinary tract infection, pneumonia, meningitis, and abscess of the appendix. Haemophilus influenzae, Escherichia coli, and Klebsiella pneumoniae were isolated. The minimum inhibitory concentrations of aztreonam for these bacteria ranged from 0.03 to 0.5 micrograms/ml. All patients were clinically and bacteriologically cured within 5-16 days of treatment. Six months after completion of therapy, patients who had had meningitis appeared to be free of any neurologic sequelae. The antibiotic was well tolerated by all patients.
氨曲南用于治疗20名被诊断患有以下任何一种感染的儿童：尿路感染、肺炎、脑膜炎和阑尾脓肿。分离出了流感嗜血杆菌、大肠杆菌和肺炎克雷伯菌。氨曲南对这些细菌的最低抑菌浓度范围为0.03至0.5微克/毫升。所有患者在治疗5至16天内临床和细菌学上均治愈。治疗结束6个月后，曾患脑膜炎的患者似乎没有任何神经后遗症。所有患者对该抗生素耐受性良好。
