Mihos Christos G, Pineda Andres M, Capoulade Romain, Santana Orlando
Cardiac Ultrasound Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Columbia University Division of Cardiology, Mount Sinai Heart Institute, Miami Beach, Florida.
Ann Thorac Surg. 2016 Oct;102(4):1400-5. doi: 10.1016/j.athoracsur.2016.04.009. Epub 2016 Jun 17.
A systematic review was conducted to assess the efficacy of mitral valve repair using glutaraldehyde-treated autologous pericardial leaflet augmentation for rheumatic mitral regurgitation (MR). Five retrospective studies were identified, which included 196 patients with moderate or greater MR. There was 1 operative death (0.5%). At a mean follow-up of 3.2 ± 2.2 years, moderate or greater MR reoccurred in 22 patients (11.2%), reoperation was required in 9 (4.6%), and the cumulative survival was 98.9%. Finally, outcomes were similar between the patients who underwent augmentation of the anterior vs the posterior mitral leaflet. Pericardial leaflet augmentation is a viable technique for the treatment of rheumatic MR.
进行了一项系统评价，以评估使用戊二醛处理的自体心包瓣叶扩大术修复风湿性二尖瓣反流（MR）的疗效。共纳入5项回顾性研究，包括196例中度或更严重MR患者。有1例手术死亡（0.5%）。平均随访3.2±2.2年时，22例患者（11.2%）出现中度或更严重MR复发，9例（4.6%）需要再次手术，累积生存率为98.9%。最后，二尖瓣前叶与后叶扩大术患者的结局相似。心包瓣叶扩大术是治疗风湿性MR的一种可行技术。
