Archiopoli Ashley, Ginossar Tamar, Wilcox Bryan, Avila Magdalena, Hill Ricky, Oetzel John
a Department of Arts & Humanities , University of Houston-Downtown , Houston , TX , USA.
b Department of Communication & Journalism , The University of New Mexico , Albuquerque , NM , USA.
AIDS Care. 2016 Dec;28(12):1607-1614. doi: 10.1080/09540121.2016.1192577. Epub 2016 Jun 20.
Despite devastating effects on health outcomes and disease progression, many people living with HIV (PLWH) are non-adherent to their medications. Medication self-efficacy is a pivotal factor in medication adherence, yet its formation and relationship with other factors are understudied. This study examines a model that considers the role of three communicative factors (patient-provider communication, social support, and social undermining) and two behavioral health factors (depression and alcohol abuse) and medication self-efficacy impacting medication adherence. Methods included a cross-sectional design using a survey questionnaire of 344 PLWH. Findings indicated that 25% of variance in medication adherence can be explained by a mediation model where depression (B = -.18) and provider-patient communication (B = .21) affect medication self-efficacy, which in turn impacts medication adherence (B = .64). Other variables, including demographics, did not add any explanatory power. These findings demonstrate the complex nature of medication adherence and the formation of medication self-efficacy.
尽管对健康结果和疾病进展有毁灭性影响，但许多艾滋病毒感染者（PLWH）不坚持服药。药物自我效能感是药物依从性的关键因素，但其形成以及与其他因素的关系尚未得到充分研究。本研究考察了一个模型，该模型考虑了三个沟通因素（医患沟通、社会支持和社会破坏）、两个行为健康因素（抑郁和酒精滥用）以及药物自我效能感对药物依从性的影响。方法包括采用对344名艾滋病毒感染者的调查问卷进行横断面设计。研究结果表明，药物依从性25%的变异可由一个中介模型解释，其中抑郁（B = -0.18）和医患沟通（B = 0.21）影响药物自我效能感，进而影响药物依从性（B = 0.64）。其他变量，包括人口统计学变量，并未增加任何解释力。这些研究结果证明了药物依从性以及药物自我效能感形成的复杂性。
