Duke University Medical Center, Department of Radiology, DUMC Box 3808, Durham, NC 27710, USA.
Duke University Medical Center, Department of Surgery, Division of Urologic Surgery & Duke Prostate Center, DUMC Box 2804, Durham, NC 27710, USA.
Future Oncol. 2016 Nov;12(21):2513-2529. doi: 10.2217/fon-2016-0142. Epub 2016 Jun 20.
Prostate cancer is the most common noncutaneous cancer in men though many men will not die of this disease and may not require definitive treatment. Active surveillance (AS) is an increasingly utilized potential solution to the issue of overtreatment of prostate cancer. Traditionally, prostate cancer patients have been stratified into risk groups based on clinical stage on digital rectal examination, prostate-specific antigen and biopsy Gleason score, though each of these variables has significant limitations. This review will discuss the potential role for prostate multiparametric MRI and targeted biopsy techniques incorporating MRI in the selection of candidates for AS, monitoring patients on AS and as triggers for definitive treatment.
前列腺癌是男性中最常见的非皮肤癌，但许多男性不会死于这种疾病，也可能不需要确定性治疗。主动监测（AS）是解决前列腺癌过度治疗问题的一种越来越被广泛应用的潜在解决方案。传统上，前列腺癌患者根据直肠指检、前列腺特异性抗原和活检 Gleason 评分的临床分期分为风险组，尽管这些变量都存在显著的局限性。这篇综述将讨论前列腺多参数 MRI 的潜在作用，以及将 MRI 纳入 AS 候选者选择、AS 监测患者和确定性治疗触发因素的靶向活检技术。
